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肢端型黑色素瘤（acral melanoma, AM）是一种起源于手掌、足底和甲下等部位的恶性皮肤肿瘤，也是亚洲人群中最主要的黑色素瘤亚型。原位AM（AM in situ, AMis）突破基底膜进入真皮发展为侵袭性AM（invasive AM, iAM）是造成患者预后变差的重要里程碑事件。然而，目前关于AMis的研究仍然十分有限，AMis向iAM的演化过程尚不清楚，免疫微环境在这一过程中发挥的作用...
Nuclear Explained – Nuclear Medicine and Radiation Technologies to Fight Against Cancer
癌症 核医学 辐射技术
2023/3/16
What does nuclear and radiation have to do in the fight against cancer? In this episode, experts explain the key role of radiation-based technologies in comprehensive cancer control.
2022年3月25日，中南大学湘雅三医院胃肠外科Ⅱ科朱晒红、朱利勇团队在《Molecular Cancer》（2020 IF: 27.401）上发表题为“Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer”的高水平论文。中南大学湘雅三医院胃肠外科Ⅱ...
Nut and peanut butter consumption and the risk of esophageal and gastric cancer subtypes
nut peanut butter esophageal cancer gastric cancer
2018/11/19
Background: Nut consumption has been associated with decreased risk of colorectal, endometrial, lung, and pancreatic cancers. Polyphenols, fiber, vitamins, and minerals in nuts may confer this observe...
Gaskins et al. study reports on a new opportunity for breast cancer prevention
gut microbiome research beneficial gut microbiota epidemiologic study
2018/11/16
Gaskins et al. (1) reports on a promising new opportunity for gut microbiome research. Dietary manipulations to promote the growth of beneficial gut microbiota are currently being investigated as a no...
Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status
biomarkers colorectal cancer inflammation metabolite ratios vitamin B-6
2018/11/13
Background: Higher plasma concentrations of the vitamin B-6 marker pyridoxal 5′-phosphate (PLP) have been associated with reduced colorectal cancer (CRC) risk. Inflammatory processes, including vitami...
Men’s health supplement use and outcomes in men receiving definitive intensity-modulated radiation therapy for localized prostate cancer
complementary and alternative medicine dietary supplements men’s health prostate cancer radiation therapy vitamins multivitamins
2018/12/19
Background: Approximately 50% of newly diagnosed cancer patients start taking dietary supplements. Men’s health supplements (MHSs), which we define as supplements that are specifically marketed with t...
Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer
colorectal neoplasms body composition body weight changes prognosis recurrence
2018/12/14
Background: Studies on the association between body mass index (BMI) and colorectal cancer (CRC) prognosis after diagnosis have yielded inconsistent results. Few studies have investigated associations...
Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer
colorectal neoplasms body composition body weight changes prognosis recurrence
2018/12/18
Background: Studies on the association between body mass index (BMI) and colorectal cancer (CRC) prognosis after diagnosis have yielded inconsistent results. Few studies have investigated associations...
High red meat intake and all-cause cardiovascular and cancer mortality: is the risk modified by fruit and vegetable intake?
fruit red meat vegetables interaction effect modification
2018/12/14
Background: High red meat consumption is associated with a shorter survival and higher risk of cardiovascular disease (CVD), cancer, and all-cause mortality. Fruit and vegetable (FV) consumption is as...
High red meat intake and all-cause cardiovascular and cancer mortality: is the risk modified by fruit and vegetable intake?
fruit red meat vegetables interaction effect modification
2018/12/18
Background: High red meat consumption is associated with a shorter survival and higher risk of cardiovascular disease (CVD), cancer, and all-cause mortality. Fruit and vegetable (FV) consumption is as...
Prospective study of serum cysteine and cysteinylglycine and cancer of the head and neck, esophagus, and stomach in a cohort of male smokers
cysteine esophageal neoplasms head and neck neoplasms stomach neoplasms upper gastrointestinal tract cancers
2018/12/14
Background:The nonessential amino acid cysteine is known to be involved in many antioxidant and anticarcinogenic pathways. Cysteinylglycine is a pro-oxidant metabolite of glutathione and a precursor o...
Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes
Busselton Health Study cancer outcomes follow-up study iron risk factors
2018/12/14
Background: Although the carcinogenic potential of iron has been shown, evidence from observational studies that have linked serum iron variables and cancer outcomes has been inconsistent.
More results but no clear conclusion on selenium and cancer
selenium cancer diabetes amyotrophic lateral sclerosis
2018/12/3
In this issue of the Journal, Hughes et al. (1) present findings from the well-known EPIC (European Prospective Investigation into Cancer and Nutrition) study that show an increased risk of hepatocell...
Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort
hepatocellular carcinoma selenium selenoprotein P prospective cohort liver cancer hepatobiliary cancer selenium status
2018/12/13
Background: Selenium status is suboptimal in many Europeans and may be a risk factor for the development of various cancers, including those of the liver and biliary tract.