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Proteolytic Regulation of CtrA, the Master Regulator of Cell Cycle in Caulobacter crescentus
Caulobacter proteolysis CtrA SciP
2014/12/9
Cell cycle progression in Caulobacter crescentus depends on the master regulator, CtrA. During the transition from swarmer to stalk cell (G1 to S phase), CtrA is degraded by the AAA+ protease ClpXP an...
Synthetic spatially graded Rac activation drives directed cell polarization and locomotion
Synthetic spatially graded Rac directed cell polarization and locomotion Molecular Networks
2012/5/2
Migrating cells possess intracellular gradients of Rho GTPases, but it is unknown whether these shallow gradients themselves can induce motility. Here we describe a new method to present cells with in...