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Period (Per1、Per2、Per3)基因广泛分布于生物体中,对许多生物的昼夜节律、细胞周期、DNA损伤修复起重要的作用。目前许多研究结果显示,Period基因是一种抑癌基因,与乳腺癌的发生密切相关,其启动子高甲基化导致了其在乳腺癌中表达下调。本文就Period基因与乳腺癌关系的研究进展进行综述。
Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts
BMI adults genetics twins international comparisons
2018/11/15
Background: Genes and the environment contribute to variation in adult body mass index [BMI (in kg/m2)], but factors modifying these variance components are poorly understood.
Changes in the nutrition and health status of young Norway spruce stands in the Krkonoše Mts. in a 17-year period
mountain forest height increment defoliation nutrients stress elements nutrient ratio
2018/3/6
For 17 Norway spruce stands located in the Krkonoše Mts. in the Czech Republic a long-term assessment of defoliation,
height increment, foliage concentration of nutrients (N, P, Ca, K, Mg) and s...
Climate-induced seasonal activity and flight period of cerambycid beetles in the Zselic forests, Hungary
abiotic factors abundance Cerambycidae activity of adultS faunistic data
2018/3/6
The longhorn beetle fauna (Coleoptera: Cerambycidae) was studied in the Zselic region (Somogy county) in Hungary
in seven consecutive years (2009–2015). In total 2,931 specimens were observed and the...
The internal state of RC4 stream cipher is a permutation over ZNZN and its state transition is effectively a transposition or swapping of two elements. How the randomness of RC4 state evolves due to i...
Changes in expression of monocarboxylate transporters, heat shock proteins and meat quality of Large White Yorkshire and Ghungroo pigs during hot summer period
Ghungroo Pig Glycolytic Rate Heat Shock Proteins (HSPs) Meat Quality Mono-carboxylate Transporters (MCTs)
2017/3/9
Present study explores the effect of hot summer period on the glycolytic rate of early post-mortem meat quality of Ghungroo and Large White Yorkshire (LWY) pig and comparative adaptability to high tem...
Effects of thermal manipulation during late incubation period on post-hatch thermotolerance in ostrich
ostrich embryo heat stress hatchability blood biochemicals epigenetic
2016/11/11
The effects of thermal manipulation (TM) during late ostrich embryonic development on hatchability, body weight, biochemical and hormonal changes, and the ability of hatching chicks to cope with therm...
Length of prematurity period in wheat cultivars determines maximum cereal aphid abundance
flowering time Metopolophium dirhodum population Rhopalosiphum padi Sitobion avenae spring wheat
2016/9/2
Maximum aphid numbers on wheat are positively related to the length of the period elapsed from immigration to the population peak. We predicted that maximum abundances on late maturing cultivars would...
Levels of fatty acids in the whole body of hens and cocks of the Cobb 500 and Ross 308 hybrid combinations at the end of the fattening period
saturated fatty acids monounsaturated fatty acids polyunsaturated fatty acids n-6 n-3
2016/9/1
In this study, we determined the levels of individual fatty acids in the whole chicken body, as well as dry matter, nitrogenic substances and fat in Cobb 500 and Ross 308 chickens after 40 days of fat...
Urinary iodine concentrations and thyroid function in adult Zimbabweans during a period of transition in iodine status
hyperthyroidism urinary iodine Zimbabwe
2016/6/1
In 1993 the compulsory iodization of salt was
introduced in Zimbabwe, a country that was previously an area
of severe iodine deficiency
Factors in Dry Period Associated with Intramammary Infection and Subsequent Clinical Mastitis in Early Postpartum Cows
Dry Period Clinical Mastitis Intramammary Infection
2016/5/20
The objective of this study was to determine cow characteristics and farm management factors during the dry period associated with early postparturient intramammary infection (IMI) and subsequent clin...
Effects of Chromium Methionine Supplementation on Blood Metabolites and Fatty Acid Profile of Beef during Late Fattening Period in Holstein Steers
Chromium Methionine Chelate, Blood Metabolites, Fatty Acids, Beef Steers, Beef Quality
2016/5/19
The objective of this study was to determine the effects of chromium methionine (Cr-Met) chelate supplementation on blood metabolites and fatty acid profile of beef from Holstein steers during late fa...
Effects of Monensin on Metabolism and Production in Dairy Saanen Goats in Periparturient Period
Monensin Dairy Goats Saanen Metabolism
2016/5/11
This trial evaluated the effects of dietary supplementation with monensin sodium on dry matter intake, metabolic parameters and milk yield and milk composition of dairy Saanen goats in the periparturi...
Outcome of home parenteral nutrition in 251 children over a 14-y period: report of a single center
home parenteral nutrition children outcome complications growth
2018/11/30
Background: Parenteral nutrition (PN) is the main treatment for intestinal failure.
Objective: We aimed to review the indications for home parenteral nutrition (HPN) in children and describe the outc...
Pumping human milk in the early postpartum period: its impact on long-term practices for feeding at the breast and exclusively feeding human milk in a longitudinal survey cohort
human milk infant feeding lactation milk expression pumping
2018/11/29
Background: Most American mothers who feed human milk (HM) now use pumps to produce some of the HM they feed. Pumping is nationally recommended, but associations between pumping and HM-feeding duratio...