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Effects of vitamin A and C and melatonin on 3-nitrotyrosine formation in guinea pig heart under lipopolysaccharide-induced stress
Lipopolysaccharide peroxynitrite 3-nitrotyrosine vitamin A vitamin C melatonin
2010/10/14
Bacterial lipopolysaccharide (LPS) triggers synthesis of nitric oxide (NO) and superoxide (O2.-). O2.- can react with NO to produce the powerful oxidant peroxynitrite (ONOO-). The presence of 3-nitrot...
Effect of classic preconditioning and diazoxide on endothelial function and O 2 and NO generation in the post-ischemic guinea-pig heart
Endothelial dysfunction Nitric oxide Ischemic preconditioning Oxygen free radicals Ischemia Reperfusion
2014/3/31
A hypothesis was tested that a reaction product between superoxide (O2
) and nitric oxide (NO) mediates post-ischemic
coronary endothelial dysfunction that ischemic preconditioning (IPC) protects...