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The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids
absorption ADME flavonoids genotype health metabolism microbiome
2018/11/12
At a population level, there is growing evidence of the beneficial effects of dietary flavonoids on health. However, there is extensive heterogeneity in the response to increased intake, which is like...
Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
milk leptin insulin the infant intestinal microbiome
2018/11/12
We read with great interest the study by Lemas et al. (1) that reported early changes in the gut microbiota composition and functions of exclusively breastfed infants born from obese mothers compared ...
Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype
malnutrition metabolome metabolic phenotype metabolome metabonomics microbiome microbiota, protein deficiency undernutrition
2018/12/18
Background: Environmental enteropathy, which is linked to undernutrition and chronic infections, affects the physical and mental growth of children in developing areas worldwide. Key to understanding ...
Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome: follow-up of a randomized controlled trial
fiber gastrointestinal microbiota metagenome microbiome prebiotic
2018/12/19
Background: In our published randomized, double-blind, placebo-controlled, 3-period crossover trial, healthy adult men (n = 21) consumed bars containing no supplemental fiber (placebo; NFC), polydextr...
Variable selection for sparse Dirichlet-multinomial regression with an application to microbiome data analysis
Coordinate descent counts data overdispersion regularized likelihood sparse group penalty
2013/6/14
With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for ea...
Variable selection for sparse Dirichlet-multinomial regression with an application to microbiome data analysis
Coordinate descent counts data overdispersion regularized likelihood sparse group penalty
2013/6/14
With the development of next generation sequencing technology, researchers have now been able to study the microbiome composition using direct sequencing, whose output are bacterial taxa counts for ea...