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The effect of microorganisms on cytokine secretion from bone marrow dendritic cells
Dendritic cells microorganisms cytokines
2010/10/14
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial ...
Curdlan Induces DC-Mediated Th17 Polarization via Jagged1 Activation in Human Dendritic Cells
adjuvant dendritic cells Notch ligand Th17 β-gulcan
2010/11/12
Background: Th17-inducing activity is carried by certain polysaccharides such as β-glucan derived from Candia albicans. Our previous studies have shown that Th1- and Th2-inducing activities can be qua...
Alarming Dendritic Cells for Allergic Sensitization
alarmins asthma danger signals dendritic cells IL-1
2010/11/12
Allergic patients mount a Th2 response to common allergens, like house dust mite (HDM), pollens, molds and animal dander. Most inhaled antigens are immunologically inert, however if these antigens are...
Interstitial and Langerhans' dendritic cells in chronic periodontitis and gingivitis
Periodontitis Gingivitis Dendritic cells CD1a Factor XIIIa
2009/10/16
The aim of the present study was to compare quantitatively the distribution of dendritic cell subpopulations in chronic periodontitis and gingivitis. Fourteen biopsies from patients with chronic perio...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...
Specific Antitumor Effects of Tumor Vaccine Produced by Electrofusion between Osteosarcoma Cell Line and Dendritic Cells in Rats
Dendritic cell osteosarcoma tumor vaccine
2009/7/15
Background: Dendritic cells (DCs) are the strongest antigen presenting cells (APCs). They can present antigen to T lymphocytes in vivo and in vitro, and induce cytotoxic T lymphocyte (CTL) reactions. ...
Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells
Potential differentiation tumor bearing mouse CD11b+Gr-1+ immature myeloid cells suppressor macrophages immunostimulatory dendritic cells
2009/5/8
Evaluation of immunosuppressive tumor-escape mechanisms in tumor-bearing hosts is of great importance for the development of an efficient tumor immunotherapy. We document here the functional charact...
Many metals and metal-containing compounds have been identified to induce various immunological disorders. In the skin, it is well known that metals contained in the dental amalgam and mercury in the ...
Dendritic cells (DC) play key rolls in various aspects of immunity. The functions of DC depend on the subsets as well as their location or activation status. Understanding developmental lineages, prec...
Dendritic Cells—Importance in Allergy—
asthma atopic dermatitis contact dermatitis Th1/Th2
2010/11/18
In this review we discuss the role of dendritic cells (DC) in the pathogenesis of allergic contact hypersensitivity (ACH) and atopic disorders, such as asthma and atopic eczema. In ACH patients, DC re...
Dendritic Cells—A Conductor of T Cell Differentiation—
dendritic cells regulatory T cells Th1 Th2 Th17
2010/11/18
Induction of different types of adaptive immune responses depending on the nature of antigens and the environmental context is crucial to cope with a variety of pathogens and concurrently to avoid pat...
Dendritic Cells-Nature and Classification
Dendritic cells Development Functional plasticity Immune response Lineage Subset heterogeneity
2010/11/18
Dendritic cells (DCs) are antigen (Ag)-presenting cells (APCs) characterized by a unique capacity to stimulate naïve T cells and initiate primary immune responses. Recent studies suggest that DCs...
Effects of Respiratory Syncytial Virus Infection on Dendritic Cells and Cysteinyl Leukotrienes in Lung Tissues of a Murine Model of Asthma
asthma cysteinyl leukotrienes dendritic cell Dermatophagoides farinae respiratory syncytial virus
2010/11/18
Background: Pulmonary dendritic cells (DCs) play critical roles in both allergy and in viral infection. Levels of cysteinyl leukotrienes (cysLTs) increase after allergen sensitization and viral infect...
High Production of IL-18 by Dendritic Cells Induced by Sera from Patients with Primary Antibody Deficiency
Common variable immunodeficiency Interleukin-18 X-linked agammaglobulinemia
2010/4/8
Predominantly antibody deficiencies are a category of primary immunodeficiency diseases, which
consist of several rare disorders such as common variable immunodeficiency (CVID) and X-linked agammaglo...
Dendritic Cells Bearing HLA-G Inhibit T-Cell Activation in Type 1 Diabetes
Dendritic cell HLA-G IFN-β (Interferon β)
2010/4/2
HLA-G is normally expressed on human trophoblast cells. It is a non-classical MHC molecule class I b. The role of HLA-G in diabetic type 1 is not known.We investigated the role of IFN-β in induction H...