搜索结果: 1-15 共查到“知识库 immunity”相关记录113条 . 查询时间(0.093 秒)
Pathogen-associated Molecular Pattern-triggered Immunity Involves Proteolytic Degradation of Core Nonsense-mediated mRNA Decay Factors During the Early Defense Response
UPF protein ubiquitination resistance gene Nonsense-mediated mRNA decay (NMD) Defense response Effective immunity
2024/1/22
Nonsense-mediated mRNA decay (NMD), an mRNA quality control process, has been implicated in plant immunity. A subset of fully spliced (FS) transcripts of Arabidopsis resistance (R) genes are reportedl...
慢性胰腺炎是一种进行性纤维化炎症疾病，其特点是炎症的反复发作和广泛的胰腺组织纤维化。慢性胰腺炎发病率逐年升高，但其发病机制尚未完全阐明。探究胰腺炎组织纤维化的诱发机制可以为胰腺炎疾病的预防和治疗开辟新的潜在策略。近日，上海中医药大学附属龙华医院杨旭光与复旦大学上海医学院的林玉丽团队展开合作研究，从基质细胞代谢过程调节免疫微环境这一新视角出发，深度剖析了慢性胰腺炎组织纤维化的诱发机制，在国际顶级免疫...
B淋巴细胞在肿瘤免疫中的研究是新近热点。在实体肿瘤中发现B细胞浸润及其构成的三级淋巴结构（Tumor-associated tertiary lymphoid structures，TLS）与抗肿瘤免疫激活、免疫治疗响应密切相关[1-3]。但是， B细胞也通过肿瘤免疫微环境与免疫调节发挥促肿瘤免疫抑制效应[4-6]，后者的研究存在较多空白[7, 8]。因此，剖析肿瘤浸润B细胞的特性及其调节功能的获...
2022年3月22日，中国科学院生物物理研究所范祖森课题组在Immunity杂志在线发表了题为"IntestinalTuft-2cellsexertantimicrobialimmunityviasensingbacterialmetaboliteN-undecanoylglycine"的论文。该研究揭示了肠道上皮细胞新亚群Tuft-2细胞通过犁鼻器受体Vmn2r26识别细菌代谢产物N-undec...
2021年8月2日，浙江大学生命科学研究院靳津课题组和浙江大学邵逸夫医院曹倩课题组合作在Immunity杂志在线发表了题为“Multiomic analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease”的研究论文，解析了微量元素硒调控CD患者Th1细胞分化...
屈前辉课题组分别在《Structure》 & 《Immunity》上报道Patch1研究及EB病毒vGPCR研究（图）
屈前辉课题组 EB病毒 生物医学研究院 Hh信号 单分子荧光实验
2023/4/17
细胞表面跨膜蛋白Patched（Ptc1）介导的Hedgehog (Hh)信号传递是调控动物形态发生的重要通路，其功能失调往往导致机体发育异常，且与基底细胞癌等恶性肿瘤的发生密切相关。穿膜12次的Ptc1蛋白主要分布于初级纤毛上。当没有配体Hh存在时，Ptc1可以通过降低细胞膜中的固醇类分子水平来抑制Hh信号通路及下游基因的转录表达。感应到Hh信号后，Ptc1从初级纤毛中向纤毛基底部位迁移，并富集...
近日，中国疾病预防控制中心病毒病预防控制所刘军研究员团队与深圳华大生命科学研究院、解放军总医院第五医学中心、北京地坛医院和深圳国家基因库等机构科学家联合在Cell子刊Immunity杂志（IF：22.5）上在线发表题为“Single-cell sequencing of peripheral blood mononuclear cells reveals distinct immune respo...
2020年6月17日,上海市免疫学研究所王宏林团队在国际免疫学顶级期刊 Immunity 发表题为“Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis”的研究论文。
Biosynthesis and regulation of salicylic acid and N-hydroxypipecolic acid in plant immunity
plant immunity Salicylic acid (SA) Biosynthesis
2024/2/4
Salicylic acid (SA) has long been known to be essential for basal defense and systemic acquired resistance (SAR). N-hydroxypipecolic acid (NHP), a recently discovered plant metabolite, also plays a ke...
A role for tocopherol biosynthesis in Arabidopsis thaliana basal immunity to bacterial infection
tocopherols tocopherol biosynthesis VTE2 Arabidopsis
2024/2/28
Tocopherols are lipid-soluble antioxidants synthesized in plastids of higher plants and other photosynthetic organisms. The four known tocopherols alpha-, beta-, gamma- and delta-tocopherol differ in ...
About Wave Implementation and its Leakage Immunity
preimage sampleable function hash and sign signature provable security
2019/5/23
Wave is a recent digital signature scheme. It is based on a family of trapdoor one-way Preimage Sampleable Functions and is proven EUF-CMA in the random oracle model under two code-based computational...
Fast Algebraic Immunity of $2^m+2$ & $2^m+3$ variables Majority Function
Fast algebraic immunity Majority function Algebraic immunity
2019/3/20
Boolean functions used in some cryptosystems of stream ciphers should satisfy various criteria simultaneously to resist some known attacks. The fast algebraic attack (FAA) is feasible if one can find ...
In-feed supplementation of clinoptilolite favourably modulates intestinal and systemic immunity and some production parameters in weaned pigs
clinoptilolite immunomodulation performance bacterial counts piglet
2016/7/6
The ban on dietary antibiotic growth promoters (AGP) in swine production has focused increasing research efforts on the development of alternative feed supplements. One such alternative to AGP is the ...
Immunity and the emergence of individuality
Immune system individual individuality organism superorganism evolutionary transition major transition symbiosis immunology philosophy of immunology complexity adaptation innate and adaptive immunity
2016/6/15
Since (Buss 1987), it has become clear that individuality is not to be considered as a given, but rather as something which needs to be explained. How has individuality emerged through evolution, and ...
The speed of change:towards a discontinuity theory of immunity?
Immunology philosophy of immunology continuity-discontinuity theory self identity self-nonself theory model molecular biology
2016/6/15
Immunology, though deeply experimental in everyday practice, is also a theoretical discipline. Recent advances in the understanding of innate immunity, how it is triggered, and how it shares features ...