搜索结果: 1-10 共查到“知识库 医学 Molecules”相关记录10条 . 查询时间(0.072 秒)
Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy
Cancer Chemotherapy Base Excision Repair DNA Repair
2015/5/25
The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of the damaged base by a DNA glycosylase creates an apurini...
Design and applications of bifunctional small molecules: Why two heads are better than one
bifunctional small molecules heads
2014/11/25
Induction of protein−protein interactions is a daunting challenge, but recent studies show promise for small molecules that specifically bring two or more protein molecules together for enhanced...
Effects of Aerobic Exercise on Lipid-Effector Molecules of the Innate Immune Response
MUCOSAL IMMUNITY ANTIMICROBIAL PEPTIDES EPITHELIAL CELLS FREE FATTY ACIDS CHOLESTERYL ESTERS AEROBIC FITNESS
2017/5/18
Consistent, moderate-to-vigorous-intensity exercise has been associated with a lower risk of upper respiratory tract infection (URI). However, the molecular basis for this apparent protection has not ...
Isatis tinctoria L. combined with co-stimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice
Isatis molecules prolongs
2013/6/26
Memory T cells present a unique challenge in transplantation. Although memory T cells express robust immune responses to invading pathogens, they may be resistant to the effects of immunosuppressive t...
The quasi-one-dimensional assembly of horseradish peroxidase molecules in presence of the alternating magnetic field
Electromagnetic field Protein molecules Assembly
2010/7/16
Here we reported the assembly of horseradish peroxidase molecules mediated by the alternating
magnetic field. The field can make quasi-one-dimensional assembly conformations. We proved the phenomenon...
Use of neonatal tolerization and chemical immunosuppression for the production of monoclonal antibodies to maturation-specific sperm surface molecules
neonatal tolerization chemical immunosuppression monoclonal antibodies
2009/2/7
Mammalian sperm acquire functional maturity as they move from the caput to the cauda epididymidis. Changes occur in the protein/glycoprotein composition of the sperm plasma membrane during this time...
Effect of macrolides on the expression of human leukocyte antigen-DR and costimulatory molecules on cultured human mononuclear cells
CD54 CD80 CD86 costimulatory molecules human leukocyte antigen-DR macrolides monocytes
2010/11/25
Although the clinical effectiveness of long-term low-dose administration of macrolides for diffuse pan- bronchiolitis, sinobronchial syndrome, chronic sinusitis and otitis media with effusion has been...
Role of adhesion molecules in eosinophil activation: A comparative study on the effect of adhesion molecules on eosinophil survival
adhesion molecule β integrin eosinophil fibronectin survival
2010/11/22
Background: Adhesion molecules participate in an important part of inflammatory process in relation to the accumulation of inflammatory cells, such as eosinophils. The expression of adhesion molecules...
A Three-Component Extraction Using Biological Molecules: An Undergraduate Organic Experiment for Prepharmacy Students
extraction assessment pre-pharmacy students organic chemistry
2018/3/22
Objectives. This experiment was designed for prepharmacy students to learn to use a separatory funnel to sequentially extract 2 components from a complex mixture, as well as develop a working knowledg...
Aquaporins in the Kidney: From Molecules to Medicine
Aquaporins the Kidney From Molecules to Medicine
2014/3/31
The discovery of aquaporin membrane water channels by Agre and co-workers (6, 7, 191, 192) answered a long-standing biophysical question of how water crosses
biological membranes specifically, and pr...