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近日,中南大学湘雅医院卫健委肿瘤蛋白质组学重点实验室陈永恒教授团队在蛋白质组学权威期刊《Molecular & Cellular Proteomics》(分子与细胞蛋白质组学,IF:7.381)上,以论著形式发表题为“Proteomics profiling reveals the molecular signatures and potential therapeutic targets of ...
Intrinsically disordered proteins in molecular recognition and structural proteomics
Protein function Protein structure Protein interactions
2015/5/26
Intrinsically disordered proteins (IDPs) are abundant in nature, being more prevalent in the proteomes of eukaryotes than those of bacteria or archaea. As introduced in Chapter I, these proteins, or p...
INTEGRATIVE SYSTEM BIOLOGY STUDIES ON HIGH THROUGHPUT GENOMICS AND PROTEOMICS DATASET
System Biology Genomics Proteomics
2015/5/26
The post genomic era has propelled us to the view that the biological systems are complex network of interacting genes, proteins and small molecules that give rise to biological form and function. The...
An integrated proteomics analysis of bone tissues in response to mechanical stimulation
bone stress biomarker discovery pathway analysis Tandem Mass Spectrometry
2015/3/5
Bone cells can sense physical forces and convert mechanical stimulation conditions into biochemical signals that lead to expression of mechanically sensitive genes and proteins. However, it is still p...
The path to preservation: Using proteomics to decipher the fate of diatom proteins during microbial degradation
The path to preservation: Using proteomics decipher the fate diatom proteins microbial degradation
2014/4/17
We drew upon recent advances in tandem mass spectrometry-based proteomic analyses in order to examine the proteins that remain after a diatom bloom enters the stationary phase, precipitates out of the...