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Pattern formation in a cell based auxin transport model with numerical bifurcation analysis
Pattern formation cell auxin transport model numerical bifurcation analysis
2012/2/28
Transport models of growth hormones can be used to reproduce the hormone accumulations that occur in plant organs. Mostly, these accumulation patterns are calculated using time step methods, even thou...
Formation of BCR Oligomers Provides a Mechanism for B cell Affinity Discrimination
Formation BCR Oligomers Provides Mechanism B cell Affinity Discrimination
2012/2/28
B cells encounter antigen over a wide affinity range. The strength of B cell signaling in response to antigen increases with affinity, a process known as "affinity discrimination". In this work, we us...
An acoustically-driven biochip - Impact of flow on the cell-association of targeted drug carriers
acoustically-driven biochip - Impact flow cell-association targeted drug carriers
2011/8/11
Abstract: The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding a...
Computing fluxes and chemical potential distributions in biochemical networks: energy balance analysis of the human red blood cell
Metabolioc networks energy balance analysis thermodynamic efficiency
2011/8/16
Abstract: The analysis of non-equilibrium steady states of biochemical reaction networks relies on finding the configurations of fluxes and chemical potentials satisfying stoichiometric (mass balance)...
SIRT1 DEFICIENCY COMPROMISES MOUSE EMBRYONIC STEM CELL DIFFERENTIATION, AND EMBRYONIC AND ADULT HEMATOPOIESIS IN THE MOUSE
Mouse Embryonic Stem Cell Hematopoietic Cell Differentiation
2015/5/21
SIRT1 (Sirtuin 1) is a founding member of a family of seven proteins and histone deacetylases. It is involved in cellular resistance to stress, metabolism, differentiation, aging, and tumor suppressio...
Effects of Altering Cell Proliferation on Hematopoietic Stem and Progenitor Cell Function
hematopoietic progenitor cell cell cycle
2015/5/21
Cell cycle checkpoints guarantee movement through the cell cycle in an appropriate manner. The spindle assembly checkpoint (SAC) ensures the proper segregation of chromosomes into daughter cells durin...
Activated Leukocyte Cell Adhesion Molecule: Expression in the Uterine Endometrium during the Estrous Cycle and Pregnancy in Pigs
Pig Pregnancy Uterus Endometrium ALCAM
2016/5/6
The pig exhibits true epitheliochorial placentation, where the fetal membrane maintains attachment throughout pregnancy but does not invade into the maternal uterine endometrium. Accordingly, the expr...
Mammary Cell Turnover under High Temperature during the Dry Period in Dairy Cows
High Temperature Dry Period Cell Cycle Apoptosis Proliferation Dairy Cow
2016/5/6
The influence of high temperature on mammary cell turnover during the dry period is still unclear. The objective of this study was to investigate mammary cell turnover and p53 protein expression in th...
A Structured Population Model of Cell Differentiation
Structured Population Model Cell Differentiationv
2011/1/5
We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it i...
Viral epidemics in a cell culture: novel high resolution data and their interpretation by a percolation theory based model
cell culture novel high resolution data interpretation
2011/1/5
Because of its relevance to everyday life, the spreading of viral infections has been of central interest in a variety of scientific communities involved in fighting, preventing and theoretically inte...
Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony
Deterministic stochastic aspects VEGF-A production
2011/1/5
A model is proposed to study the process of hypoxia-induced angiogenesis in cancer cells. The model accounts for the role played by the vascular endothelial growth factor (VEGF)-A in regulating the ox...
Some thoughts on the ontogenesis in B-cell immune networks
Some thoughts the ontogenesis B-cell immune networks
2011/1/5
We are interested in modeling theoretical immunology within a statistical mechanics flavor: focusing on the antigen-independent maturation process of B-cells, in this paper we try to revise the proble...
Asymptotic and bifurcation analysis of wave-pinning in a reaction-diffusion model for cell polarization
Asymptotic bifurcation analysis wave-pinning reaction-diffusion model
2011/1/5
We describe and analyze a bistable reaction-diffusion (RD) model for two interconverting chemical species that exhibits a phenomenon of wave-pinning: a wave of activation of one of the species is init...
Spontaneous contractility--mediated cortical flow generates cell migration in 3-dimensional environments
Spontaneous contractility--mediated cortical flow generates migration 3-dimensional environments
2010/11/15
We present a generic model of cell motility generated by acto-myosin contraction of the cell cortex. We identify analytically dynamical instabilities of the cortex and show that they trigger spontaneo...
Stochastic modeling of gene activation and application to cell regulation
Stochastic modeling gene activation application regulation
2010/11/15
Transcription factors (TFs) are key regulators of gene expression. Based on the classical scenario in which the TF search process switches between one-dimensional motion along the DNA molecule and fre...