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Experimental Standards: evaluating success in stem cell biology
experiment stem cells epistemic history
2011/9/5
This paper aims to bring the epistemic dimensions of stem cell experiments out of the background, and show that they can be critically evaluated. After introducing some basic concepts of stem cell bio...
A new framework for identifying combinatorial regulation of transcription factors: a case study of the yeast cell cycle
framework identifying combinatorial regulation transcription factors yeast cell cycle
2010/11/15
By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activ...
Expression of Human Papillomavirus Type 16 E7 Is Sufficient To Significantly Increase Expression of Angiogenic Factors But Is Not Sufficient To Induce Endothelial Cell Migration
Neovascularization inhibitors Tumor suppressor proteins Cancer
2015/5/21
Human papillomavirus 16 (HPV 16) causes cancer. Two viral oncoproteins of HPV 16, E6 and E7, are consistently expressed in these cancers. HPV 16 E6 and E7 proteins target p53 and Rb family members, re...
Eicosanoid Regulation of Hematopoietic Stem and Progenitor Cell Function
AMD3100 G-CSF NSAID EP receptor Meloxicam
2015/5/21
dult hematopoietic stem cells (HSC) are routinely used to reconstitute hematopoiesis after myeloablation; however, transplantation efficacy and multilineage reconstitution can be limited by inadequate...
XPC DNA REPAIR PROTEIN REGULATION IN THE CONTEXT OF THE G1/S CELL CYCLE CHECKPOINT
XPC DNA repair retinoblastoma protein cell cycle
2015/5/21
DNA is subject to various types of damage that can impair cellular function or cause cell death. DNA damage blocks normal cellular processes such as replication and transcription and can have catastro...
Interspecies Somatic Cell Nuclear Transfer Technique for Researching Dog Cloning and Embryonic Stem Cells
Canine Interspecies Porcine Somatic cell Nuclear Transfer
2016/5/5
Large quantities of high-quality recipient oocytes with uniform cytoplasm are needed for research in the promising field of somatic cell nuclear transfer (SCNT) and embryonic stem cell research. In ca...
Expression Patterns of Germ Cell-specific Phosducin-like 2 during Testicular and Ovarian Development in Chickens
Chickens In situ Hybridization Pdcl2 qRT-PCR
2016/5/5
Phosducin (PDC) is a photoreceptor cell-specific protein that is phosphorylated by cyclic nucleotide-dependent protein kinase. PDC and PDC-like proteins (PDCL, PDCL2, and PDCL3) are members of a conse...
PCR-SSCP of Serum Lysozyme Gene (Exon-III) in Riverine Buffalo and Its Association with Lysozyme Activity and Somatic Cell Count
Polymorphism Lysozyme Gene SSCP Buffalo Association SCC Sequencing
2016/5/5
Serum lysozyme gene is one of the important genes influencing the immune system as its product can cause lysis of bacterial cell wall by cleaving the peptidoglycan layer. The present investigation on ...
Effect of Sex Steroid Hormones on Bovine Myogenic Satellite Cell Proliferation, Differentiation and Lipid Accumulation in Myotube
Myogenic Satellite Cells Steroids Serum Stem Cells Bovine
2016/5/4
Myogenic satellite cells (MSCs) are adult stem cells that activate and differentiate into myotubes. These stem cells are multipotent as they transdifferentiate into adipocyte-like cells, nerve cells a...
Construction of Mammalian Cell Expression Vector for pAcGFP-bFLIP(L) Fusion Protein and Its Expression in Follicular Granulosa Cells
c-FLIP(L) pAcGFP-N l Recombinant Plasmid Follicular Granulosa Cell
2016/5/4
FLICE inhibitory protein (FLIP) is one of the important anti-apoptotic proteins in the Fas/FasL apoptotic path which has death effect domains, mimicking the pro-domain of procaspase-8. To reveal the i...
THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN INCREASES P34CDC2 PHOSPHORYLATION AND ENHANCES CELL SURVIVAL AND PROLIFERATION BY PROTECTING THE WEE1 KINASE FROM DEGRADATION BY CASPASE-3
p34Cdc2 Survivin Wee1 Caspase-3 Apoptosis
2015/5/21
The anti-apoptotic protein Survivin and the cyclin-dependent kinase p34Cdc2 are involved in cell cycle progression and apoptosis. Activation of Cdc2 is required for its pro-apoptotic activity, which c...
STAT PROTEIN REGULATION OF FOXP3 EXPRESSION AND INFLAMMATORY CYTOKINE PRODUCTION IN T HELPER CELL SUBSETS
Stat proteins Stat4 cytokines inflammation Foxp3
2015/5/21
ThedifferentiationofnaïveCD4+TcellsintosubsetsofThelpercells(Th)isan
essentialprocessthatimpactshostdefenseandthepathogenesisofimmunemediated
diseases.Signaltransducersandactivatorsoftranscript...
Somatic Cell Nuclear Transfer of Oocytes Aspirated from Postovulatory Ovarian Follicles of Superovulated Rabbits
Nuclear Transfer Oocyte Rabbit Follicle Somatic Cell
2016/5/3
The aim of this study was to evaluate if oocytes, aspirated from postovulatory ovarian follicles of superovulated rabbits 14 h post-hCG administration, could be efficiently used as ooplasm recipients ...
Relationship between Developmental Ability and Cell Number of Day 2 Porcine Embryos Produced by Parthenogenesis or Somatic Cell Nuclear Transfer
Blastomeric Fragmentation Developmental Ability Embryo Quality Parthenogenesis Porcine Somatic Cell Nuclear Transfer
2016/4/29
In vitro produced porcine embryos have potential application in reproductive biotechnology. However, their development potential has been very low. This study evaluated the in vitro developmental abil...
Effects of Donor Cell Passage, Size and Type on Development of Porcine Embryos Derived from Somatic Cell Nuclear Transfer
Donor Cell Passage Size Nuclear Transfer Porcine
2016/4/29
The aim of this study was to investigate the effects of donor cell passage, size and type on the development of nuclear transfer embryos. Porcine cumulus cells, fetal fibroblasts and oviductal epithel...