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环状胶粒是一种典型的非凸胶体,是构建复杂多层级材料的新型自组装基元,其独特的拓扑结构使其单粒子及其组装体可能具有不同寻常的光电磁性能,因而为材料构建提供了很多新的可能性。但是,环状胶体的研究仍缺少普适性且可规模化的合成方法,导致其材料性能的探索有限。
本发明提出了一种基于生物知识和网络拓扑结构的药物重定位方法和系统,包括网络构建模块、特征学习模块、模型训练模块、药物重定位模块以及结果展示模块,其中,所述网络构建模块将生物网络数据构建为异构信息网络,特征学习模块执行服务器计算指令,获得药物和疾病的生物特征矩阵和网络特征矩阵,模型训练模块获取输入参数后在服务器中训练药物发现模型,药物重定位模块在得到药物重定位模型后执行药物重定位指令,最后将药物重定...
Computing the intersection between two parametric surfaces (SSI) is one of the most fundamental problems in geometric and solid modeling. Maintaining the SSI topology is critical to its computation ro...
In this paper, we investigate the energy minimization model arising in the ensemble Kohn–Sham density functional theory for metallic systems, in which a pseudo-eigenvalue matrix and a general smearing...
Part of the motivation of this paper comes from the recent paper [W. Guo and H.-Z. Zhou, SIAM J. Control Optim., 57 (2019), pp. 1890–1928], where an adaptive control approach was used to estimate in r...
The finite-time stabilization problem is considered for a class of multi-input multi-output nonlinear systems composed of several different subsystems that are coupled with unknown nonlinearities, pos...
This paper is concerned with both observability and observers for a class of systems described by the two-dimensional hyperbolic PDEs with superlinear boundary conditions which can exhibit chaos. The ...
This article studies input design of kernel-based regularization methods for linear dynamical systems, which has been formulated as a nonconvex optimization problem with the criterion being a scalar m...
In this work, we construct a novel numerical method for solving the multimarginal optimal transport problems with Coulomb cost. This type of optimal transport problem arises in quantum physics and pla...
Advertising becomes one of the most popular ways of monetizing an online transaction platform. Usually, sponsored advertisements are posted on the most attractive positions to enhance the number of cl...
Based on the perfectly matched layer (PML) technique, this paper develops a highly accurate boundary integral equation (BIE) solver for acoustic scattering problems in locally defected layered media i...
This paper is devoted to studying two multiobjective problems for stochastic degenerate parabolic equations. The first one is a hierarchical control problem, in which the controls are classified into ...
In this paper, we prove that the \(L^p(\mathbb {R}^d)\) norm of the maximal truncated Riesz transform in terms of the \(L^p(\mathbb {R}^d)\) norm of Riesz transform is dimension-free for any \(2\le p<...
As a specific type of shape gradient descent algorithm, shape gradient flow is widely used for shape optimization problems constrained by partial differential equations. In this approach, the constrai...
Face recognition has always been courted in computer vision and is especially amenable to situations with significant variations between frontal and profile faces. Traditional techniques make great st...

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