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Abnormal Hemoglobins Associated with Beta-Globin Gene in Antalya Province, Turkey
Abnormal hemoglobins Antalya beta-thalassemia Turkish population
2010/2/24
Some of the abnormal hemoglobin variants found are unstable and some of them cannot be detected by simple electrophoretic examinations. Our findings suggest that abnormal hemoglobins are more frequent...
Circadian variations in liver gene expression: Relationships to drug action
Circadian variations liver gene expression drug action
2009/12/24
Chronopharmacology is an important but under-explored aspect of therapeutics. Rhythmic
variations in biological processes can influence drug action, including pharmacodynamic
responses, due to ci...
On the potential for integrating gene expression and metabolic flux data
Systems biology gene expression metabolic flux modeling
2009/12/24
Computational strategies, that integrate genomic-level information and metabolic flux data, have improved both prediction of metabolic fluxes and metabolic network identification. Due to the tight int...
Stent-Based Gene Therapy。
About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT’s Daniel Anderson and Robert Langer for gene therapy, the i...
A Common Polymorphism of Upstream Transcription Factor 1 Gene is associated with Lipid Profile: A Study in Chinese Type 2 Diabetes Families
dyslipidemia genetic epidemiology single nucleotide polymorphism type 2 diabetes mellitus upstream transcription factor
2009/10/30
Upstream transcription factor 1 (USF1) is capable of controlling various members in glucose and lipid metabolism pathways. Much evidence suggests that the rs3737787 polymorphism in the USF1 gene may l...
Basic Studies on Gene Therapy with Ultrasound.
Effects of chronic ingestion of catechin-rich green tea on hepatic gene expression of gluconeogenic enzymes in rats
chronic ingestion catechin-rich green tea hepatic gene expression of gluconeogenic enzymes rats
2009/5/8
Normal rats were given catechin-rich green tea as drinking fluid and the effects on hepatic gene expression were examined. The results of DNA microarray analysis and quantitative real-time reverse t...
DNA microarray analysis of changes in gene expression induced by 1,25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells
DNA microarray analysis gene expression 1,25-dihydroxyvitamin D3 promyelocytic leukemia HL-60 cells
2009/3/2
Using a DNA microarray, we analyzed about 16,600 genes for changes in expression associated with the differentiation of human promyelocytic leukemia HL-60 cells induced by 1α,25-dihydroxyvitamin D3 ...
Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation
HCN gene expression Nkx2.5-positive cardiomyocytes murine embryonic stem cells
2009/3/2
Changes in the expression of hyperpolarization-activated cyclic nucleotide (HCN)-gated channels and If currents during the differentiation of embryonic stem cells into cardiac cells remain unknown. ...
Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motility
Possible involvement A gene Helicobacter pylori colonization stomach motility
2009/3/2
H. pylori is a gram-negative bacterium associated with gastric inflammation and peptic ulcer and considered a risk factor for gastric cancer in its natural habitat. However, the energy metabolism of...