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Prevention by Cortisone of Aspirin -Induced Gastric Ulceration in The Rat
Prevention Cortisone Aspirin-Induced Gastric Ulceration The Rat
2009/12/3
The effect of cortisone on the experimental gastric ulceration produced by intraperitoneal injection of aspirin in the rat is studied. Cortisone has significantly prevented the appearance of aspirin_ ...
Distribution of Tamoxifen in Rat Tissues During Steady-State Treatment
kidneys Tamoxifen Tissues Rat
2009/7/2
Tamoxifen citrate (TAM), a nonsteroidal antiestrogen, is a drug of choice in the endocrine treatment for all stages of breast cancer in both pre and postmenopausal patients. The tissue distrubution of...
The Effects of Nitric Oxide on Rat Stomach Injury Induced by Acetylsalicylic Acid
Nitric oxide stomach injury acetylsalicylic acid microscopy
2009/5/21
Aim: Acetylsalicylic acid (ASA, aspirin), which is one of the most frequently used drugs in the world, causes severe gastric mucosal injury. Nitric oxide (NO) is synthesized from L-arginine by nitric ...
Intraventricular gabapentin is antinociceptive and enhances systemic morphine antinociception in rat tail flick test
Intraventricular Gabapentin Tail- flick
2010/4/26
Background: Gabapentin has been recently considered as an analgesic in neurpathic pain through spinal site of action. In addition co-administration of low dose of morphine with gabapentin, is proposed...
Facilitating effects of morphine dependence on spatial learning and memory in rat
Morphine dependence Spatial learning and memory Morris water maze
2010/4/19
The effect of morphine on spatial learning and memory is controversial. In the present
study, the male rats were used to evaluate the effect of morphine dependence and cold
water swimming on spatial...
PROTECTIVE EFFECT OF VITAMIN D3 IN METHYLPREDNISOLONE ACETATE (MPA) INDUCED LOSS OF BONE METABOLISM MARKERS AND BONE MINERAL DENSITY IN THE LUMBAR SPINE OF RAT
Methylprednisolone acetate vitamin D3 bone markers metabolism
2010/4/7
Although some vitamins have been shown to prevent glucocorticoids induced osteoporosis in short time, the magnitude of this effect remains to be clarified. The aim of this study was to evaluate protec...
Spasmolytic effect of Vitis vinifera leaf extract on rat colon
Vitis vinifera Antispasmodic Colon
2010/4/7
Vitis vinifera (grape) leaf has been used traditionally to treat diarrhea and its extract induces relaxation in rat aorta and uterus. The aim of present study was to investigate the effect of grape le...
Simultaneous determination of metoprolol, propranolol and phenol red in samples from rat in situ intestinal perfusion studies
Propranolol Metoprolol Phenol red liquid chromatography Permeability
2010/2/3
Single-pass intestinal perfusion technique (SPIP) is the most used classic technique employed in the study of intestinal absorption of compounds in which a non-absorbable marker such as phenol red is ...