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Motility potential of macaque epididymal sperm: the role of protein phosphatase and glycogen synthase kinase-3 activities
Monkey spermatozoa enzymes caput caudal
2009/2/18
Human and monkey ejaculated sperm contain protein phosphatase-1 (PP1), PP1 inhibitor 2 (12), and glycogen synthase kinase-3 (GSK-3). Inhibition of ejaculated human sperm protein phosphatase (PP) a...
Changes in Sperm Glycogen Synthase Kinase-3 Serine Phosphorylation and Activity Accompany Motility Initiation and Stimulation
Epididymis protein kinase B phosphoinositide 3-kinase
2008/12/22
Sperm motility is regulated by protein phosphorylation. We have shown that the signaling kinase, glycogen synthase kinase-3 (GSK-3), is present in spermatozoa. In somatic cells, GSK-3 is regulated b...
Evidence for a Role of Glycogen Synthase Kinase-3ß in Rodent Spermatogenesis
Testis meiosis tubule culture Rim11p
2008/12/19
Glycogen synthase kinase-3ß (GSK-3ß) regulates cell metabolism, cell cycle, and cell fate through the phosphorylation of a diverse array of substrates. Herein, we provide evidence that s...