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Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
A computational assessment of the independent contribution of changes in canine trabecular bone volume fraction and microarchitecture to increased bone strength with suppression of bone turnover
trabecular bone bone strength suppressed bone turnover
2014/12/4
This study addressed the effects of changes in trabecular microarchitecture induced by suppressed bone turnover—including changes to the remodeling space—on the trabecular bone strength–volume fractio...
Increased strontium uptake in trabecular bone of ovariectomized calcium-deficient rats treated with strontium ranelate or strontium chloride
strontium ranelate dietary calcium ovariectomized rats
2014/12/4
Based on clinical trials showing the efficacy to reduce vertebral and non-vertebral fractures, strontium ranelate (SrR) has been approved in several countries for the treatment of postmenopausal osteo...
Expression of Glucose Transporter 4 (GLUT4) is Increased by Cinnamaldehyde in C2C12 Mouse Muscle Cells
Glucose Transporter type 4 Cinnamaldehyde Real-Time Polymerase Chain Reaction Diabetes Mellitus Insulin
2015/10/10
Background:: In diabetes mellitus because of the absence or insufficient sensitivity to insulin, glucose transporter protein in cell membrane, glucose transporter 4, is decreased. GLUT4 is the major g...
Correlation between increased urinary serotonin levels and coronary artery disease in cigarette smoking patients
Smoking serotonin 5-HT urine coronary platelet
2010/10/14
Platelets secrete serotonin (5-hydroxytryptamine), which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and the proliferation of smooth muscle cells. We therefore m...
Correlation of the intraocular pressure with increased intracranial pressure in rabbits
Intracranial pressure intracranial pressure rabbits
2009/12/30
Although measurement of intracranial pressure by noninvasive methods has been suggested, but mainly invasive methods are used for this purpose-Increase in episcleral venous pressure can be expected to...
Effects of Increased Respiratory Resistance on Maximal O2 Uptake and Anaerobic Threshold during Incremental Exercise Tests
O2 uptake Anaerobic threshold Exercise test
2009/6/26
This study was undertaken to assess whether maximal O2 uptake (VO2max) can be used as an index of measuring aerobic capacity under the condition of increased respiratory resistance. Seven male subject...
Increased Lipid Peroxidation and Decreased Antioxidant Response in Serum and Cerebrospinal Fluid in Acute Ischemic Stroke
Ischemic stroke oxidative stress cerebrospinal fluid malondialdehyde total antioxidant capacity
2009/6/17
Background and Aim: The pathogenesis of brain damage in ischemic stroke is highly complex. The aim of the present study was to investigate the presence of oxidative stress in ischemic stroke and to de...
Are Lymphoblastoid Cell Lines Suitable to Study Increased SMN Gene Expression by Histone Deacetylase Inhibitors?
Spinal muscular atrophy survival motor neuron gene histone deacetylase inhibitors treatment
2009/6/16
Aim: In this preliminary study, we aimed to analyze the effect of sodium butyrate (NB) and phenylbutyrate (PB), belonging to the class of histone deacetylase (HDAC) inhibitors, on lymphoblastoid cell ...
Elevated Platelet Activation in Patients with Atopic Dermatitis and Psoriasis: Increased Plasma Levels of β-Thromboglobulin and Platelet Factor 4
atopic dermatitis platelet factor 4 platelets psoriasis β-thromboglobulin
2010/11/17
Our results show that blood platelets are activated in patients with AD or psoriasis, suggesting that activated platelets play a role in the pathomechanism of chronic skin inflammation. Furthermore, p...
Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology
β-adrenergic receptor agonists anti-IgE antibody anti-interleukin-5 monoclonal antibody asthma corticosteroids leukotriene inhibitors theophylline
2010/11/24
The mainstay of chronic asthma management consists of using pharmacological agents that induce broncho-dilatation, such as short-acting β-adrenergic receptor agonists (bronchodilators or relievers), a...
Positional Effect of Amino Acid Replacement on Peptide Antigens for the Increased IFN-γ Production from CD4T Cells
analogue peptide complementarity determining region 3 interferon gamma peptide antigens T-cell antigen receptor
2010/11/19
Background: Based on the fact that site-specific amino acid replacement on peptide antigens stimulated T cell clones to produce increased amount of IFN-γ, we investigated this structure-function relat...
Serum Levels of Th2-Type Immunoglobulins are Increased in Weanling Mice Subjected to Acute Wasting Protein-Energy Malnutrition
Protein-energy malnutrition Serum immunoglobulins
2010/4/16
The bulk of our knowledge on immunosuppression in malnutrition comes from the experiments done on cell-mediated immunity. However, malnutrition-induced modifications of humoral immunity have been less...