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Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
apolipoproteins atherosclerosis cholesterol coronary heart disease diet
2018/11/28
Background: In general populations, the effects of dietary cholesterol on blood cholesterol concentrations are modest. However, the relation is stronger in those with an ɛ4 allele in the apolipop...
Punctuated equilibrium in statistical models of generalized coevolutionary resilience: How sudden ecosystem transitions can entrain both phenotype expression and Darwinian selection
coevolution cognitive paradigm gene expression information theory
2015/7/29
We argue, using a mathematical model based on asymptotic limit theorems of probability theory, that mesoscale ecosystem resilience shifts can entrain punctuated events of gene expression and other cog...
EFFECTS OF CHOLINE KINASE ACTIVITY ON PHOSPHOLIPID METABOLISM AND MALIGNANT PHENOTYPE OF PROSTATE CANCER CELLS
hypoxia cancer HIF
2015/5/25
High choline uptake and increased choline kinase activity have been reported in many cancers. This has motivated the use of choline as a biomarker for tumor imaging. Tumors in general are heterogeneou...
Inflammatory Genes and Psychological Factors Predict Induced Shoulder Pain Phenotype
CHRONIC,PAIN MUSCLE,PAIN INFLAMMATION,SNP IL1B TNF/LTA,REGION IL6
2017/5/24
The pain experience has multiple influences, but little is known about how specific biological and psychological factors interact to influence pain responses. The current study investigated the combin...
Effects of Eccentrically and Concentrically Biased Training on Mouse Muscle Phenotype
MUSCLE PLASTICITY MUSCLE FIBER TYPOLOGY MOUSE MUSCLE PROTEOME MYOSIN HEAVY CHAINS ECCENTRIC CONTRACTION
2017/7/17
Introduction: The molecular adaptations specifically induced by different muscle contraction types have only been partially elucidated. We previously demonstrated that eccentric contractions in human ...
Successful Treatment of Life-Threatening Cerebral Bleeding Associated with Disseminated Intravascular Coagulation Using Recombinant Human Soluble Thrombomodulin in a Patient with Mixed Phenotype Acute Leukemia with t (9; 22) (q34; q11.2); Bcr-Abl1
Mixed Phenotype Acute Leukemia with t (9 22) (q34 q11.2) Bcr-Abl1
2013/1/29
Recently, mixed phenotype acute leukemia (MPAL) with t (9; 22) (q34; q11.2); bcr-abl1 was described as one kind of acute leukemia of ambiguous lineage in the 2008 World Health Organization Classificat...
Relationship between PON1 phenotype and headache duration in migraine patients
Paraoxonase arylesterase phenotype lipid hydroperoxide
2011/3/22
available data on the activity of paraoxonase-1 (PON1) in patients suffering from migraine without aura (MWoA) is scarce. The present study was conducted to fulfill the objective of investigating the ...
Adhesion rates and chondrocyte phenotype in monolayer cultures under the influence of Collagen type II and IGF-I
Chondrocyte phenotype Collagen type II IGF-I Integrin Immunoelectron microscopy
2009/12/25
When grown in monolayer culture at low density and with the addition of serum, cartilage cells dedifferentiate or are overgrown by fibroblast-like cells. The aim of this study was to optimize the cult...
Congo Red-binding Protein in Rough-phenotype Aggregatibacter actinomycetemcomitans is Amyloid-like Fiber
Aggregatibacter actinomycetemcomitans Congo red-binding Amyloid
2010/1/21
Aggregatibacter actinomycetemcomitans is a pathogen associated with chronic and aggressive periodontitis and extra-oral infections. Fresh isolates of A. actinomycetemcomitans are fimbriated, forming s...
A New Phenotype in the PhosphOĞLUcomutase 1 (PGM1) System,PGM1*W32
PGM1 henotype arephenotype
2009/7/2
Red cell phosphOĞLUcomutase 1 (PGM1) enzyme, which is a phosphotransferase, has 3 common and 31 rare phenotypes. In this study, we have identified a new phenotype for this enzyme which has not be...
Characterization of Catalytic Phenotype of b-Galactosidase From LacI Mutant,E.Coli CSH-36,as a Tool For The Management of Lactose Intolerance
lactose intolerance b-Galactosidase E.coli purification kinetics
2009/6/30
Objectives: Lactose intolerance is a common public health problem with 5-100% prevalance among different populations of the world. Use of b-galactosidase to reduce the lactose content in food or consu...
Adhesion of Beta1 Integrin to Fibronectin Regulates CAM-DR Phenotype via p21WAF1/cip1 in HL60 Acute Myeloid Leukemia (AML) Cells
Apoptosis CAM-DR fibronectin cell cycle
2009/6/16
Aims: Drug resistance is a major obstacle for a successful cancer therapy. Cell adhesion mediated drug resistance (CAM-DR) is a novel type of drug resistance and generated via interaction of cancer ce...
Genotype-Phenotype Analysis of Mutation R778L in the ATP7B Gene
genotype-phenotype mutation ATP7B Wilson’s disease
2009/4/1
Wilson’s disease (WD), an autosomal recessive disorder of copper transport, usually presents with symptoms of the liver or central nervous system. The known disease-caused mutations identified in the ...
Congo Red-binding Protein in Rough-phenotype Aggregatibacter actinomycetemcomitans is Amyloid-like Fiber
Aggregatibacter actinomycetemcomitans Congo red-binding
2010/12/1
Aggregatibacter actinomycetemcomitans is a pathogen associated with chronic and aggressive periodontitis and extra-oral infections. Fresh isolates of A. actinomycetemcomitans are fimbriated, forming s...
Correlation of CASA velocity and linearity parameters with sperm mobility phenotype in turkeys
CASA velocity linearity parameters sperm mobility phenotype turkeys
2008/12/25
Since all domestic turkeys are produced through artificial insemination, a measurable sperm characteristic that would be predictive of fertility would allow for the culling of poor males, resultin...