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山东大学医学院医学遗传学课件(七年制)mitochondrial Disorder。
Nuclear transfer of mitochondrial DNA in colon and rectal cancer
Nuclear transfer mitochondrial DNA colon and rectal cancer
2017/4/27
Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal G...
Cornell University researchers have confirmed a genetic link between mitochondrial DNA (mtDNA), which is passed on from the mother, and some forms of autism spectrum disorder (ASD).Previous research s...
Effect of hypoenergetic feeding and refeeding on muscle and mononuclear cell activities of mitochondrial complexes I–IV in enterally fed rats
mitochondrial complexes I–IV electron transport chain rats
2016/6/13
Previous studies suggested that cell energetics are
altered by malnutrition.
Effect of Neem Oil on Sperm Mitochondrial Activity
Normozoospermia Neem Oil Sperm Mitochondrial Activity
2015/7/15
It is a known fact that neem oil has some effect on motility of sperm. Motility of sperm depends on mitochondrial activity present in mid-piece of sperm. In the present study, the mitochondrial activi...
Impaired Mitochondrial Function and Reduced Energy Cost as a Result of Muscle Damage
ATP PRODUCTION EXERCISE-INDUCED MUSCLE DAMAGE MAGNETIC RESONANCE SPECTROSCOPY NEUROMUSCULAR ELECTROSTIMULATION
2017/4/19
Purpose: Although it has been largely acknowledged that isometric neuromuscular electrostimulation (NMES) exercise induces larger muscle damage than voluntary contractions, the corresponding effects o...
Altering DNA Base Excision Repair: Use of Nuclear and Mitochondrial-Targeted N-Methylpurine DNA Glycosylase to Sensitize Astroglia to Chemotherapeutic Agents
DNA repair astrocytes
2014/12/12
Primary astrocyte cultures were used to investigate the modulation of DNA repair as a tool for sensitizing astrocytes to genotoxic agents. Base excision repair (BER) is the principal mechanism by whic...
Plasma Levels of Mitochondrial DNA in Patients Presenting to the Emergency Department with Sepsis
Sepsis SIRS mtDNA mitochondrial DNA inflammation
2014/11/28
Introduction Elevated levels of plasma mitochondrial DNA (mtDNA) have been reported in trauma patients, and may contribute to the systemic immune response. We sought to determine the plasma levels of ...
Method for Controlled Mitochondrial Perturbation during Phosphorus MRS in Children
31P-MRS MUSCLE,MITOCHONDRIA CHILDREN EXERCISE,PERCEPTION
2017/5/24
Insulin resistance is increasingly prevalent in children and may be related to muscle mitochondrial dysfunction, necessitating development of mitochondrial assessment techniques. Recent studies used 3...
Hydrostatic pressure effects on eel mitochondrial functioning and membrane fluidity
Hydrostatic pressure mitochondrial function membrane fluidity migration animal yellow eel pressure acclimatization aerobic metabolism
2009/6/2
Aerobic metabolism which is required for long swimming activities during the eel's spawning migration at depth, is a potential target for pressure effects due to its components located in the inner mi...
Celecoxib Enhances the Chemotherapeutic Response of Cisplatin and TNF-α in SiHa Cells through Reactive Oxygen Species-Mediated Mitochondrial Pathway
cervical cancer apoptosis celecoxib cisplatin TNF-α mitochondria
2009/4/20
Recently, many studies have shown that celecoxib induces apoptosis in various cancer cells by different mechanisms depending on the cell type. This study examined the effect of the selective COX-2 inh...
Human sperm mitochondrial function related to motility:a flow and image cytometric assessment
Human sperm mitochondrial function motility cytometric assessment
2009/2/23
Current evaluation of male fertility, routinely estimated by sperm count, motility, and morphology, provides only crude information about the fertility state of individuals. Both flow and image cyto...
Differential effects of(+)and(-)gossypol enantiomers on mitochondrial function and proliferation of cultured TM4 cells
Gossypol isomer TM4 cells mitochondria
2009/2/23
The in vitro effects of (+) and (-)gossypol enantiomers on the mitochondrial functions of mouse transformed Sertoli, TM4 cells were investigated by monitoring mitochondrial rhodamine 123 accumulat...
Effects of cyclophosphamide on selected cytosolic and mitochondrial enzymes in the epididymis of the rat
cyclophosphamide selected cytosolic mitochondrial enzymes epididymis rat
2009/2/23
The anticancer and immunosuppressive drug cyclophosphamide is extensively used in clinical practice and is known to alter fertility in man. We showed previously that treatment of male rats with lo...