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Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids
fat malabsorption fat balance lipolysis
2016/5/27
Pancreatic enzyme replacement therapy frequently
fails to correct intestinal fat malabsorption completely in
cystic fibrosis (CF) patients. The reason for this failure is
unknown.
Cycling Exercise Training Alleviates Hypoxia-Impaired Erythrocyte Rheology
EXERCISE HYPOXIA ERYTHROCYTE HEMORHEOLOGY
2017/4/13
Purpose: Physical exercise or hypoxic exposure influences hemorheology and acid–base homeostasis. Band 3 protein in erythrocytes modulates cells’ rheological properties and anion transport ability. Th...
Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation
Shp2 pERK Bradycardia
2015/5/25
Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is requir...
IMPAIRED CARDIOVASCULAR RESPONSES TO GLUCAGON-LIKE PEPTIDE 1 IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITUS
metabolism GLP-1 obesity diabetes
2015/5/22
Recent advancements in the management of systemic glucose regulation in obesity/T2DM include drug therapies designed to utilize components of the incretin system specifically related to glucagon-like ...
Association of Cardiorespiratory Fitness with Elevated Hepatic Enzyme and Liver Fat in Japanese Patients with Impaired Glucose Tolerance and Type 2 Diabetes Mellitus
Cardiorespiratory fitness hepatic enzyme non-alcoholic fatty liver abdominal obesity insulin resistance
2015/5/5
No study has so far determined whether a favorable level of cardiorespiratory fitness (CF) contributes to a reduced risk of elevated hepatic enzymes and a high degree of liver fat in patients having v...
Quantification of the Impaired Cardiac Output Response to Exercise in Heart Failure: Application of a Non-Invasive Device
Heart failure cardiac output oxygen uptake exercise testing
2015/4/23
An impaired cardiac output (CO) response to exercise is a hallmark of chronic heart failure (CHF), and the degree to which CO is impaired is related to the severity of CHF and prognosis. However, prac...
Intramuscular Fat Infiltration Contributes to Impaired Muscle Function in COPD
MRI SPECTROSCOPY MUSCLE QUALITY MUSCLE WEAKNESS AND MOBILITY
2017/4/19
Muscle weakness is a prevalent complication in chronic obstructive pulmonary disease (COPD). Atrophy does not fully explain muscle weakness in this population. The recent focus on fat infiltration and...
Impaired Mitochondrial Function and Reduced Energy Cost as a Result of Muscle Damage
ATP PRODUCTION EXERCISE-INDUCED MUSCLE DAMAGE MAGNETIC RESONANCE SPECTROSCOPY NEUROMUSCULAR ELECTROSTIMULATION
2017/4/19
Purpose: Although it has been largely acknowledged that isometric neuromuscular electrostimulation (NMES) exercise induces larger muscle damage than voluntary contractions, the corresponding effects o...
Is the Soleus a Sentinel Muscle for Impaired Aerobic Capacity in Heart Failure?
CHRONIC HEART FAILURE SKELETAL MUSCLE SOLEUS EXERCISE CAPACITY
2017/4/14
Purpose: Skeletal muscle wasting is well documented in chronic heart failure (CHF). This article provides a more detailed understanding of the morphology behind this muscle wasting and the relation be...
Research With Cognitively Impaired Participants
informed consent vulnerable populations cognitively impaired code of federal regulations safeguards decision making capacity
2014/12/3
Illnesses that cause cognitive impairment are a considerable health problem in the United States. These include Alzheimer's disease, Huntington's chorea, cerebrovascular disease, psychiatric disorders...
A Comparison of Auditory Perception in Hearing-Impaired and Normal-Hearing Listeners: An Auditory Scene Analysis Study
Auditory Scene Analysis Sensorineural Hearing Loss Hearing
2015/10/9
Background: Auditory scene analysis (ASA) is the process by which the auditory system separates individual sounds in natural-world situations. ASA is a key function of auditory system, and contributes...
Biomechanical analysis of the final strides of the approach and the take-off by visually impaired class F12 and F13 long jumpers
2D-DLT ANALYSIS STRIDE LENGTH JOINT ANGULAR KINEMATICS VISUAL ACUITY TECHNIQUE
2013/10/1
Despite of the level of visual aquity, European Records in long jumping are greater in class F12 (visual acuity 2/60) than class F13 (visual acuity 6/60) both in males and females. The aim of the pres...
Hyperhomocysteinemia and Increased Oxidative Stress Levels Are Associated with Impaired Membrane Fluidity of Red Blood Cells in Hypertensive and Normotensive Men: An Electron Spin Resonance Investigation
Homocysteine Oxidative Stress 8-Iso-Prostaglandin F2α
2013/1/29
Hyperhomocysteinemia and oxidative stress may be strongly linked to hypertension, atherosclerosis and other cardiovascular diseases. The present study was performed to investigate possible relationshi...
Prenatal and Postnatal Exposures to 1-Methyl-4-phenyl-1,2,3,6-tetra Hydropyridine (MPTP) Impaired Mouse Midbrain Dopamine System and May Produce a Predisposing and Inducing Model for Parkinson’s Disease
Parkinson’s Disease Midbrain -Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)
2013/1/29
Dopamine cell bodies in the substantia nigra of the midbrain and with their terminals projecting to the neostriatum form the nigrostriatum and these dopamine neurons degenerate in Parkinson’s disease ...
Could Mean Platelet Volume Predicts Impaired Reperfusion and In-Hospital Major Adverse Cardiovascular Event in Patients with Primary Percutaneous Coronary Intervention after ST-Elevation Myocardial Infarction?
Myocardial infarction Heart Catheterization Reperfusion
2009/12/18
Background: Due to the positive relation between platelet size and platelet reactivity, a high value of the mean platelet volume (MPV) is an independent risk factor to predict acute myocardial infarct...