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Substituting whole grain for refined grain: what is needed to strengthen the scientific evidence for health outcomes?
grain health outcomes scientific evidence
2018/11/13
Worldwide, dietary guidelines have adopted the recommendation of consuming whole grain as part of a healthy diet. Ideally, dietary guidelines are based on convincing evidence, established by multiple ...
Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study
Diet whole grain refined grain
2016/6/1
Although current dietary guidelines for Americans
recommend increased intake of grain products to prevent coronary
heart disease (CHD), epidemiologic data relating wholegrain
intake to the risk of ...
Whole-grain wheat consumption reduces inflammation in a randomized controlled trial on overweight and obese subjects with unhealthy dietary and lifestyle behaviors: role of polyphenols bound to cereal dietary fiber
bioavailability ferulic acid inflammation obesity wholegrain wheat
2018/12/20
Background: Epidemiology associates whole-grain (WG) consumption with several health benefits. Mounting evidence suggests that WG wheat polyphenols play a role in mechanisms underlying health benefits...
The effects of a whole grain–enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome1,2,3
Whole-grain foods metabolic syndrome weight loss fiber
2009/4/20
Background: Whole-grain foods are associated in observational studies with a lower body mass index and lower cardiovascular disease (CVD) risk. However, few clinical trials have tested whether incorpo...
THE EFFECT OF ENVIRONMENTAL CONDITIONS ON ERGOSTEROL AND TRICHOTHECENE CONTENT OF NATURALLY CONTAMINATED OAT GRAIN
trichothecenes ergostero oats cultivars environmental conditions
2010/12/22
Oat plants, similar to other cereals, are susceptible to invasion by fungal pathogens and saprophytes, but the severity of disease symptoms and the extent of fungal growth depend to a considerable deg...
Whole- and refined-grain intakes and the risk of hypertension in women 1,2,3
Dietary intake whole grains refined grains hypertension epidemiology
2008/12/16
Background: Prospective studies linking whole- and refined-grain intakes with the risk of hypertension, a major cardiovascular disease risk factor, remain limited.Objective: We aimed to determine whet...
Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study
Dietary fiber whole grain colorectal cancer fiber sources cohort study
2008/12/12
Background: Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsis...
Whole-grain consumption is associated with a reduced risk of noncardiovascular, noncancer death attributed to inflammatory diseases in the Iowa Women's Health Study 1,2,3,4
Whole-grain foods carbohydrate fiber inflammation
2008/12/9
Background: It has recently been shown that oxidative stress, infection, and inflammation are predominant pathophysiologic factors for several major diseases. Objective: We investigated the associatio...
Whole-grain intake and carotid artery atherosclerosis in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study1,2,3
Atherosclerosis cereals diet ethnic groups cohort studies Doppler ultrasound
2008/12/9
Background: Whole-grain intake has been shown to be inversely associated with cardiovascular events, but an association with atherosclerosis is less well established. Objective: We sought to evaluate ...
Whole-grain rye and wheat foods and markers of bowel health in overweight middle-aged men
Wheat rye dietary fiber
2016/12/30
Three 4-wk interventions were undertaken in a randomized crossover design with 28 overweight men aged 40–65 y who had no history of bowel disease. Against a background intake of 14 g dietary fiber (DF...
Whole-grain and fiber intake and the incidence of type 2 diabetes
Diet grain whole grains
2016/12/29
Epidemiologic evidence of a preventive effect of whole grain against type 2 diabetes is mainly based on data from women. Information specific to men and women is needed.
Whole-grain foods, dietary fiber, and type 2 diabetes: searching for a kernel of truth
Whole-grain foods dietary fiber
2016/12/29
Tracing the historical development of a scientific concept is a difficult and often subjective exercise. In the field of dietary research, however, the possibility that something of physiologic import...
Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study
Whole grain diet nutrition
2017/1/4
Increased intake of whole-grain foods has been related to a reduced risk of developing diabetes and heart disease. One underlying pathway for this relation may be increased insulin sensitivity.
Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women
Whole grains refined grains dietary fiber
2017/1/4
Although increased consumption of dietary fiber and grain products is widely recommended to maintain healthy body weight, little is known about the relation of whole grains to body weight and long-ter...
Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study
Whole grain fruit and vegetables all-cause mortality
2017/1/4
Recent epidemiologic study results showed that subjects who had high intakes of whole-grain foods had lower risks of death and heart disease than did subjects who had low intakes. However, the finding...