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Changes in Exhaled Nitric Oxide Measured by Two Offline Methods Predict Improvements in Bronchial Hyperresponsiveness after Inhaled Steroid Therapy in Japanese Adults with Asthma
asthma bronchial hyperresponsiveness FeNO offline method
2010/11/16
The mean of duration of observation was 406 days. There were significant relationships between ΔlogPC20Ach and logPC20Ach (r = -0.877, P < 0.001), FeNOs (r = 0.465, P = 0.002), and FeNOc (r = 0.524, P...
Relationship between Exhaled Nitric Oxide Measured by Two Offline Methods and Bronchial Hyperresponsiveness in Japanese Adults with Asthma
asthma bronchial hyperresponsiveness exhaled nitric oxide offline method
2010/11/17
Levels of eNOs and eNOc were correlated with the degree of bronchial hyperresponsiveness to acetylcholine in adult asthmatics treated with inhaled corticosteroids. Our findings suggest that offline mo...
Interleukin-4 is involved in allergen-induced airway eosinophilic inflammation and bronchial hyperresponsiveness independent of genetic background
bronchial hyperresponsiveness eosinophils IgE interleukin-4 mice
2010/11/26
The role of interleukin (IL)-4 in the development of allergen-induced airway inflammation and bronchial hyperresponsiveness (BHR) is still controversial. To investigate the role of IL-4 in the develop...
Increase of Exhaled Nitric Oxide (eNO) after Methylene Diphenyl Diisocyanate (MDI) Exposure in Isocyanate Workers with Bronchial Hyperresponsiveness
challenge test inhalation challenge isocyanates occupational asthma
2010/11/19
Fourteen of 22 symptomatic isocyanate workers showed BHR and five of these 14 developed an asthmatic response upon challenge with methylene diphenyl diisocyanate (MDI). In comparison with the group wi...
Role of neutral endopeptidase in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs
active sensitization bronchial hyperresponsiveness endotoxin histamine neutral endopeptidase substance P
2010/11/29
To investigate effects of endotoxin on allergic airway diseases, we studied bronchial responsiveness to histamine (HI) and substance P (SP) in actively sensitized and non-sensitized guinea pigs 24 h a...