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Correspondence of folate dietary intake and biomarker data
NHANES olate folic acid dietary assessment measurement error prevalence
2018/11/14
Background: Public health concerns with regard to both low and high folate status exist in the United States. Recent publications have questioned the utility of self-reported dietary intake data in re...
Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate
soluble fiber fermentation pentadecanoic heptadecanoic liver long-chain fatty acid
2018/11/14
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15:0) and heptadecanoic acid (17:0)], which are consider...
Biomarker identified for likely aggressive,early stage breast cancer
Biomarker likely aggressive early stage breast cancer
2017/4/27
The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk ‘in situ’ lesions, an e...
Dietary biomarker evaluation in a controlled feeding study in women from the Women’s Health Initiative cohort
carotenoids doubly labeled water energy fatty acids folate human feeding
2018/11/12
Background: Controlled human feeding studies are necessary for robust nutritional biomarker development and validation. Previous feeding studies have typically evaluated single nutrients and tested re...
Nanopolymer-modified protein array can pinpoint hard-to-find cancer biomarker
Nanopolymer-modified protein array cancer biomarker
2016/11/29
A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases.
Glycoproteins are formed when sugars attach...
Salivary Biomarker Responses to Two Final Matches in Women’s Professional Football
Soccer hormones saliva T/C ratio RPE stress immune response
2016/7/7
The aim of this study was to examine the link between salivary concentrations of cortisol, testosterone, immunoglobulin A (IgA) and the rate of perceived exertion (RPE) as a measure of internal load a...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/3
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study
C-reactive protein diet GlycA glycoproteins inflammation nuclear magnetic resonance spectroscopy sodium excretion
2018/12/13
Background: The extent to which dietary sodium intake may confer alterations in the inflammatory status is unclear. GlycA is a novel proton nuclear magnetic resonance spectroscopy-measured biomarker o...
Developing Biomarker Arrays Predicting Sleep and Circadian-Coupled Risks to Health
Arrays Predicting Sleep Health
2017/3/10
The impact of advances in sleep and circadian sciences over
the last 20 years on medicine, health, and public safety has
been limited in part by the lack of availability of objective
tools capable ...
Biomarker Discovery in Early Stage Breast Cancer Using Proteomics Technologies
Biomarker Proteomics
2015/5/26
Among women in the United State, breast cancer is the most common cancer
diagnosed in women with approximately 200,000 new cases reported each year and the
second leading cause of cancer-related dea...
2-Hour Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker
Pulmonary embolism outpatient risk-stratification Risk stratification malignancy prognosis decision rule treatment
2014/11/28
Objectives The purpose of this study was to determine whether a new accelerated diagnostic protocol (ADP) for possible cardiac chest pain could identify low-risk patients suitable for early discharge ...
Identification of Reduced Circulating Haptoglobin Concentration as a Biomarker of the Severity of Pulmonary Embolism: A Nontargeted Proteomic Study
pulmonary embolism reduced circulating haptoglobin concentration
2014/11/28
Risk stratification of patients with pulmonary embolism (PE) may identify patients at high risk of early death who may benefit from more intensive surveillance or aggressive therapy. Nontargeted prote...
A New Biomarker for Hepatocellular Damage: Plasma Cell-Free DNA
Hepatocellular Damage Cell-Free DNA
2013/1/28
Background: Accumulating evidence has suggested that cell-free DNA (cf-DNA) enters the circulation following cell apoptosis or necrosis. An increased level of cf-DNA fragments has been found in the bl...
Is plasma vitamin C an appropriate biomarker of vitamin C intake? A systematic review and meta-analysis
appropriate biomarker vitamin C
2008/4/23
As the primary source of dietary vitamin C is fruit and to some extent vegetables,
the plasma level of vitamin C has been considered a good surrogate or predictor of vitamin C intake
by fruit and ve...
Osteopontin: A Potential Biomarker for Successful Bee Venom Immunotherapy and a Potential Molecule for Inhibiting IgE-mediated Allergic Responses
biomarker clustering mechanism microarray osteopontin (OPN) venom immunotherapy (VIT)
2010/11/19
Venom immunotherapy (VIT) is proven to be curative for insect allergy, but the mechanisms and the biomarkers associated with clinical efficacy remain elusive. We report herein the discovery of a leadi...