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PM2.5水溶性和有机组分对肺上皮细胞损伤及COPD相关基因和蛋白表达影响
PM2.5 肺上皮细胞 氧化应激 COPD
2016/12/16
为了检测大气PM2.5对正常肺上皮细胞(BEAS-2B)的损伤作用和慢性阻塞性肺病(COPD)相关基因及蛋白的表达变化,将PM2.5的不同组分对肺上皮细胞进行染毒24 h后,通过MTT、荧光探针、Western Blot、单细胞凝胶电泳、实时荧光定量PCR、ELISA等方法检测细胞损伤、COPD相关基因和蛋白表达的变化情况.结果发现,PM2.5可造成肺上皮细胞活性降低,且呈剂量依赖性,PM2.5的...
Survival Analysis of Victims of Sulfur Oxide Air Pollution Suffering from COPD or Asthma in Yokkaichi, Japan, in Relation to Predisposing Exposure
COPD Asthma Air Pollution Sulfur Oxide Pulmonary Function Survival Analysis
2013/3/11
To investigate the relationships between clinical findings and symptoms and the survival of patients with Yokkaichi Asthma, in relation to predisposing sulfur dioxide (SO2) exposure, we examined recor...