搜索结果: 1-15 共查到“基因工程 research”相关记录20条 . 查询时间(0.125 秒)
2023年6月8日，中国科学院深圳先进技术研究院合成生物学研究所马迎飞课题组在国际期刊核酸研究（Nucleic Acids Research）发表题为 “Global transmission of broad-host-range plasmids derived from the human gut microbiome” 的文章。该工作深度分析并揭示了大量人肠道质粒，首次鉴定出一系列未知的宽...
Science Partner Journal BioDesign Research is an online-only Open Access journal published in affiliation with Nanjing Agricultural University (NAU) and distributed by the American Association for the...
近日，新疆农业科学院核技术生物技术研究所陈果副研究员在国际期刊《Nucleic Acids Research》（IF = 19.160）杂志在线发表了题为《A novel active transposon creates allelic variation through altered translation rate to influence protein abundance》的研究论文。...
浙江大学生命科学研究院2022年5月30日黄俊实验室在Nucleic Acids Research上发文报导了RNF4调控复制叉翻转及维持基因组稳定性的分子机制（图）
黄俊 复制叉翻转 维持基因 分子机制
2022/10/25
2022年5月30日，浙江大学生命科学研究院黄俊实验室在Nucleic Acids Research杂志上在线发表了题为“RNF4 controls the extent of replication fork reversal to preserve genome stability”的研究论文，揭示了细胞调控复制叉翻转及维持基因组稳定性的分子机制。
生命活动需要氧化反应提供能量，这一过程同时会产生活性氧物质（ROS）。ROS能诱导多种DNA氧化损伤，其中最常见的是8-oxo-7,8-dihydro-2'-deoxyguanosine (OG)，被视为氧化压力的标志物。如果没有被及时修复，OG可能引起G→T突变，与多种癌症、神经退行性疾病和衰老相关。除此之外，OG也有类似于表观遗传修饰的作用，可以通过几种不同的方式调控基因表达，例如OG的修复中...
黄胜林课题组《Advanced Science》和《Nucleic Acids Research》揭示环形RNA癌症特异表达和作用并构建RNA剪接位点数据库（图）
环形RNA 癌症 肽 生物学
2023/4/17
RNA 剪接（RNA splicing）是真核生物 RNA 转录后加工的必要环节，是导致转录组多样性和复杂性的关键步骤。不同的 RNA 剪接方式可产生不同类型的剪接位点，包括线性剪接位点、反式剪接位点（环形RNA）和融合位点（融合基因）。因此，一个基因往往可产生多种形式的转录本，阐明转录本的具体信息，是了解基因结构和功能机制的重要基础。其中，环形RNA是一类具有特殊环状结构的RNA分子。目前研究表...
首都医科大学江涛教授团队在Clinical Cancer Research发文阐述脑胶质瘤细胞纯度的临床、基因组学与生物学意义
首都医科大学 江涛教授团队 Clinical Cancer Research 脑胶质瘤 细胞纯度 基因组学 生物学
2018/1/17
北京市神经外科研究所江涛教授团队联合中国医科大学第一附属医院吴安华教授团队于2017年10月在Clinical Cancer Research（IF：9.619）上发表论文，题目为“Tumor Purity as an Underlying Key Factor in Glioma”。该研究通过整合5个数据库、2249例脑胶质瘤组织样本的基因表达谱数据及对应的临床、基因拷贝数、基因突变等多维组学数...
Tricky grass genome sequenced after two decades of investment and research（图）
Tricky grass genome sequenced after two decades investment research
2017/12/19
Imagine if as you read this article, blocks of text kept rearranging themselves, recombining and repeating, seemingly at random. Now imagine those blocks of text are genes. You might have some idea of...
2017细胞命运和疾病基因组结构戈登学术会议（The 2017 Gordon Research Conference on Genome Architecture in Cell Fate&Disease ）
2017 细胞命运和疾病基因组结构戈登 学术会议
2017/2/14
Accumulating evidence suggest that genomes are organized non-randomly into complex 3D configurations that vary according to cell type, stage of development, differentiation and disease status. The pri...
2017生态与进化基因组学戈登学术会议（The 2017 Gordon Research Conference on Ecological and Evolutionary Genomics）
2017 生态与进化基因组学戈登 学术会议
2017/2/14
The 2017 Gordon Research Conference on Ecological and Evolutionary Genomics will highlight recent advances in our understanding of the genomic basis of adaptation and the interaction between organisms...
NSF awards $44 million for genomic research on range of plants,many economically important
NSF $44 million genomic on range of plants economically important
2016/11/4
To advance the basic science needed to improve agricultural practices, reduce demands on environmental resources, and address climate change challenges, the National Science Foundation (NSF)'s Plant G...
CCNY research gleans climate change insight from lizard genome
CCNY gleans climate change insight lizard genome
2016/8/1
Using genomic data from three lizard species, City College of New York-led researchers gleaned insights not available before on the impact of climate change on the distribution of animal populations i...
University of Texas (UT) at Arlington researchers, working in parallel with researchers at the University of Utah, examined three genes that control multiple color phenotypes, or appearances, in pige...
The Michael Cameron Fund, a trust fund administered by The University of Queensland, welcomed a new generation member to their board last week in order to continue supporting research into Down syndro...
A $50 million Federal Government project that aims to transform the storage of research data has revealed the location of its first five nodes ?in Sydney, Brisbane, Canberra, Adelaide and Hobart.