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Our brains are charged with the task of directing most of the processes needed for our bodies to function. As such, they consume roughly 20% of our body’s metabolic energy, even while we’re resting.
Therapeutic brain modulation with targeted large neutral amino acid supplements in the Pah-enu2 phenylketonuria mouse model
phenylketonuria inborn error of metabolism large neutral amino acids mouse model neurotransmitters brain biochemistry treatment
2018/12/18
Background: Phenylketonuria treatment consists mainly of a Phe-restricted diet, which leads to suboptimal neurocognitive and psychosocial outcomes. Supplementation of large neutral amino acids (LNAAs)...
Investigation of the subunit compositi on and the pharmacology of the mitochondrial ATP-dependent K + channel in the brain
ATP-dependent potassium channel Ischemic preconditioning Mitochondrial nitric oxide synthase mtNOS Sulfonylurea recepto
2014/3/31
Selective activation of mitoK
AT P
channels can protect the brain or cultured neurons against a variety of anoxic or metabolic challenges.
However, little is known about the subunit composition or ...