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Obstacles and Circumvention Strategies for Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors
gene therapy hematopoietic stem cells sickle cell disease
2015/5/21
High-efficiency transduction of hematopoietic stem cells (HSCs) by recombinant adeno-associated virus serotype 2 (AAV2) vectors is limited by (i) inadequate expression of cellular receptor/co-receptor...
Characterization of Hepatitis C Virus Infection of Hepatocytes and Astrocytes
exosome IL-18, 3D live cell imaging
2015/5/21
Approximately 2.8% of the world population is currently infected with hepatitis C virus (HCV). Neutralizing antibodies (nAbs) are often generated in chronic hepatitis C patients yet fail to control th...