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Modulation of epidermal growth factor receptor function by mutations within the actin -binding domain
Genes actin internalization growth factors tyrosine phenylalanine glutamic acid phenylalanine residues
2014/12/11
The generation of site-directed mutants within the actin binding domain of the EGF receptor modulates receptor function in internalization and ligand binding. In addition, truncation of the EGFr at re...