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Correlation of del13q, del11q and Trisomy 12 with Laboratory and Clinical Features of Chronic Lymphocytic Leukemia in Iranian Patients
Chronic lymphocytic leukemia Chromosomal aberrations Rai stages CD markers Iran
2015/9/21
Background: There is a strong association between chromosomal abnormalities and laboratory features and clinical course of the B-cell chronic lymphocytic leukemia (B-CLL). The aim of this study was to...
Comparison between Deferoxamine and Combined Therapy with Deferoxamine and Deferiprone in Iron Overloaded Thalassemia Patients
Thalassemia major Deferoxamine Deferiprone Chelation therapy
2015/9/21
Background: Iron overload is the main cause of morbidity and mortality in patients with beta thalassemia major. Effective and convenient iron chelation remains one of the main targets of clinical mana...
Detection and Prevalence of Polyoma Virus BK among Iranian Kidney Transplant Patients by a Novel Nested-PCR
BK virus Renal transplant recipients Prevalence Iran
2015/9/21
Background: BK virus is an increasingly recognized pathogen in transplant recipient patients associated with nephropathy and emerged as a cause of allograft failure linked to immunosuppressive regimen...
Serum total sialic acid, lipid peroxidation, and glutathione reductase levels in patients with rheumatoid arthritis
Sialic acid malondialdehyde (MDA) glutathione reductase rheumatoid arthritis
2010/10/14
The changes in the serum sialic acid levels, total lipid peroxidation products (MDA), and glutathione reductase activity were estimated in patients with rheumatoid arthritis. Serum Sialic acid is know...
Correlation between increased urinary serotonin levels and coronary artery disease in cigarette smoking patients
Smoking serotonin 5-HT urine coronary platelet
2010/10/14
Platelets secrete serotonin (5-hydroxytryptamine), which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and the proliferation of smooth muscle cells. We therefore m...
Genetic signature in TB patients sheds light on disease
Genetic signature TB patients disease
2010/8/26
Medical Research Council (MRC) scientists have uncovered a ‘genetic signature’ in the blood of patients with active tuberculosis (TB). This discovery could not only serve as the basis of future diagno...
Predictors of Long-term Outcome in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A single center registry (THCR)
Acute coronary syndrome Outcome PCI
2010/4/2
Background: This study sought to access differences in long-term (9 months) outcomes between Acute Coronary Syndrome (ACS) patients who undergo early intervention compared to Percutaneous Coronary Int...
Evaluation of phenytoin pharmacokinetics in neurotrauma patients
Neurotrauma Pharmacokinetic Free fraction Neurotrauma
2010/4/2
Previous studies have suggested that drug metabolism may be altered in patients with severe neurotrauma. The purpose of this prospective study was to observe the alteration of phenytoin pharmacokineti...
Nitric Oxide and Trace Metals in Relation to Haemoglobin F Concentration in Nigerian Sickle Cell Disease Patients
Sickle cell disease trace metals haemoglobin F oxidants
2010/2/24
Sickle cell disease (SCD) is an inherited haemoglobin (Hb) disorder associated with vaso-occlusive events, oxidative stress, high energy demand, and endothelial dysfunction. The endothelium plays a ce...
Comparison of serum levels of IL-6, IL-8, TNF-?, C reactive protein and heat shock protein 70 in patients with active and inactive Behçet's disease
chemokine C-reactive protein cytokine heat shock protein interleukin Behç et's disease
2010/2/24
The results of our study suggest that serum IL-6, IL-8, TNF-, and CRP levels are increased in patients with active Behçets disease. HSP 70 levels in both active and inactive disease groups were...
Pharmacokinetic behavior of Amikacin in 31 Iranian critically ill septic patients
Amikacin Sepsis Critically ill patient ICU
2010/1/6
The pharmacokinetic behavior of amikacin and predictive performance of Sawchuk-Zaske dosing method, have been prospectively evaluated in 31 (16 male, 15 female) critically ill septic patients of mean ...
The relationship between pharmacokinetic variables and pharmacodynamic profiles of bolus versus continuous infusion of furosemide in critically ill patients
Furosemide Pharmacokinetics Pharmacodynamic Bolus Infusion
2010/1/5
In this investigation, the pharmacokinetic variables of continuous infusion and intermittent bolus injection of furosemide and the possible relationship between its pharmacokinetic characteristics and...
This investigation determined that vitamin C intake of C.W. was higher than O.P. , S. C. and C. Statistically, there was a significant difference between C.W. and C. Blood ascorbic acid levels of O.P....
Effect of multiple factors on success rate of high dose radioiodine therapy (>150µCi/gr) in 164 patients with hyperthyroidism
multiple factors high dose radioiodine therapy hyperthyroidism
2010/1/4
Background: Radiodine therapy (RIT) for hyperthyroidism is increasingly used as a therapy of choice in most of the patients. Effect of multiple factors on the result of therapy was noted. This study t...
STUDY OF SEX,AGE AND BLOOD GROUPS (ABO,Rh) DISTRIBUTIONS IN THALASSEM IA PATIENTS IN IRAN
SEX AGE AND BLOOD GROUPS DISTRIBUTIONS THALASSEM PATIENTS IRAN
2009/12/31
Thalassemias, because of climatic, geographic and ecological conditions, are the most common among the genetically endemic in Iran, especially m provinces adjacent to the Caspian Sea and the Persian G...