搜索结果: 31-45 共查到“医学 interleukin-1 b”相关记录48条 . 查询时间(0.019 秒)
Interleukin-4 is involved in allergen-induced airway eosinophilic inflammation and bronchial hyperresponsiveness independent of genetic background
bronchial hyperresponsiveness eosinophils IgE interleukin-4 mice
2010/11/26
The role of interleukin (IL)-4 in the development of allergen-induced airway inflammation and bronchial hyperresponsiveness (BHR) is still controversial. To investigate the role of IL-4 in the develop...
Interleukin-10 inhibits the production of inflammatory cytokines by antigen-stimulated mononuclear cells from asthmatic patients
bronchial asthma granulocytemacrophage colony stimulating factor interferon-γ interleukin-1β interleukin-2 interleukin-5 interleukin-10
2010/11/25
Bronchial asthma, characterized by chronic airway inflammation, involves many inflammatory cytokines. Interleukin (IL)-10 is a potent inhibitor of cytokine synthesis. Thus, the effects of IL-10 were e...
Interleukin-4 and interleukin-13 induce fibronectin production by human lung fibroblasts
fibronectin human lung fibroblast interleukin-4 interleukin-13 remodeling
2010/11/25
The results showed that IL-4 and IL-13 induced fibronectin production in a time- and a concentration-dependent manner. Anti-transforming growth factor (TGF)-β1 antibody (ab) inhibited TGF-β1-induced f...
Low-dose exogenous interleukin (IL)-12 enhances antigen-induced interferon-γ production without affecting IL-10 production in asthmatics
bronchial asthma Dermatophagoides farinae interferon-γ interleukin-10 interleukin-12 peripheral blood mononuclear cells
2010/11/25
The production of IFN-γ by PBMC was significantly enhanced by incubation with IL-12 in both patient groups (P < 0.05), while IL-12 did not affect the production of IL-10 in either group. Lymphocyte pr...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
Blocking the CD154-CD40 interaction with anti-CD154 antibody differentially regulates interleukin-4 synthesis in T cells and IgE production in B cells
CD154 CD40 germline Cε IgE interleukin-4
2010/11/25
Using severe combined immunodeficiency mice engrafted with peripheral blood mononuclear cells from atopic patients, we analyzed the regulatory effects of anti-CD154 antibody on the in vivo induction o...
Neutrophils, interleukin-17 and obstructive airway disease
airway inflammation asthma chemokine chronic obstructive pulmonary disease cytokine eosinophil macrophage protease T lymphocyte
2010/11/24
There is increasing evidence that an exaggerated accumulation of activated neutrophils is linked to the clinical course of obstructive airway diseases, such as asthma and chronic obstructive pulmonary...
Interleukin-18 is associated with the severity of atopic dermatitis
atopic dermatitis bronchial asthma IgE interferon-γ interleukin-18 interleukin-18 promoter
2010/11/24
The plasma IL-18 level was elevated, particularly in patients with atopic dermatitis. As the clinical severity of atopic dermatitis increased, the plasma IL-18 level also tended to increase. These fin...
Structural and functional analysis of a new cytokine, ML-1 (interleukin-17F)
airway inflammation cytokine network interleukin-17 family mitogen-activated protein kinase
2010/11/24
Recent large-scale sequencing of the human genome has facilitated novel gene discovery. A novel gene, ML-1 (interleukin (IL)-17F), was identified from a human expressed sequence tag (EST) sequence, a ...
Inhibition of nasal mucosal eosinophils after immunotherapy is associated with a decrease in interleukin-13 mRNA and vascular cell adhesion molecule-1 expression
adhesion molecule allergic rhinitis apoptosis immunotherapy interleukin-13
2010/11/22
Analysis of the clinical data confirmed that the proportion of patients who showed greater than 60% improvement in symptoms (47 and 15%) and in rescue medication (79 and 10%) were significant for the ...
Prostaglandin D2 and interleukin-5 reduce CRTH2 surface expression on human eosinophils
CRTH2 eosinophils interferon-γ interleukin-4 interleukin-5 prostaglandin D2
2010/11/22
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified. Because PGD2 was reported to have chemotac...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...
The Role of Interleukin-9 in Asthma
airway hyperresponsiveness asthma interleukin-9 interleukin-9 receptor mucus overproduction
2010/11/19
Interleukin (IL)-9 is a pleiotropic Th2 type cytokine which has been shown to play an important role in the pathogenesis of bronchial asthma. This review will concentrate on the structure, the source,...
Short-term stimulation with interleukin (IL)-4 enhances purified protein derivative-induced production of an eosinophil chemotactic lymphokine, but suppresses IL-5 production
eosinophil chemotactic lymphokine granulocyte—macrophage colony stimulating factor interferon-γ interleukin-4 interleukin-5 RANTES
2010/11/29
The effect of interleukin (IL)-4 on eosinophil chemotactic lymphokine (ECL) production from peripheral blood mononuclear cells (PBMC) stimulated with purified protein derivative (PPD) was examined. Th...
PREDICTIVE SIGNIFICANCE OF SERUM INTERLEUKIN-10 FOR ACUTE GRAFT VERSUS HOST DISEASE PRIOR TO ALLOGENEIC BONE MARROW TRASPLANTATION
Bone marrow transplantation interleukin-10 graft versus host disease bone marrow transplantation
2010/2/4
Interleukin-10 (IL-10) is a potent immunosuppressor which inhibits alloantigenic T cell response. IL-10 is also an anti-inflammatory endogenous cytokine. To investigate the predictive significance of ...