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Reversal of Endotoxin-Induced Hypotension by Inhibition of Inducible Nitric Oxide Synthase Activity is Associated with Improved Oxidative Status in Rat Heart,Aorta and Mesenteric Artery
Rat endotoxin hypotension inducible nitric oxide synthase lipid peroxidation
2009/6/19
Overproduction of reactive oxygen and nitrogen species leads to oxidative stress and decreased total antioxidant capacity, which is responsible for high mortality from several diseases such as endotox...
Adjuncts (Tramadol and Magnesium) Potentiate Impulse Inhibition by a Local Anaesthetic in Isolated Frog Siatic Nerves?
Bupivacaine magnesium tramadol compound nerve action potential frog sciatic nerve
2009/6/19
Aim: In clinical use, the addition of adjuncts (magnesium or tramadol) to local anesthetic agents is used for different reasons. However, reports about the effect of magnesium plus bupivacaine and of ...
Inhibition of nitric oxide synthase on brain oxygenation in anesthetized rats exposed to hyperbaric oxygenhernia
HBO oxygen toxicity nitric oxide drug hyperbaric nitric oxide synthase animal rat
2009/6/9
Nitric oxide (NO) production is involved in the development of oxygen toxicity of the central nervous system (CNS) since inhibition of nitric oxide synthase (NOS) significantly protects animals from h...
Delayed effect of nitric oxide synthase inhibition on the survival of rats after acute decompression
Decompression Animal rat Decompression Sickness enzymology mortality
2009/6/3
AIM: The formation of bubbles in the blood stream together with the ensuing sickness after rapid decompression is assumed to depend on the physiological condition of the vascular system. In order to g...
IN VIVO HEMATOPOIETIC CELL ENGRAFTMENT IS MODULATED BY DPPIV/CD26 INHIBITION AND RHEB2 OVEREXPRESSION
Hematopoiesisen Progenitor cells mTOR
2015/5/21
Hematopoietic cell transplantation (HCT) is an important modality used to treat patients with hematologic diseases and malignancies. A better understanding of the biological processes controlling hema...
PLA2 inhibition by lignocaine: Is it clinically relevant?
Decompression illness drugs treatment
2009/5/18
The place of lignocaine administration for DCI
treatment seems to be well established. The rationale for its
use is a putative anti-inflammatory effect of the drug, most
probably due to its ability...
Inhibition of Endotoxin-Induced Hepatotoxicity by Melatonin in Rats
endotoxin liver melatonin necrosis oxidative stress tumor necrosis factor α
2009/4/29
Bacterial endotoxin or lipopolysaccharide causes extensive damage to various organs including the liver. This is due to an increased production of tumor necrosis factor α induced- reactive interme...
Inhibition of Pigmentation due to a Copper-Containing Enzyme, Tyrosinase, by Oxalates and Aromatic Sulfinates
tyrosinase pigmentation inhibitor oxalates
2009/3/23
It has been revealed that pigmentation based on the oxidative polymerization of 3,4-dihydroxyphenylalanine (dopa) by the action of a copper-containing enzyme, tyrosinase, is suppressed by free oxalic ...
Inhibition or Stimulation of the Vertical Growth of the Facial Complex, Its Significance to Treatment
Vertical Growth Facial Complex Significance to Treatment
2009/3/12
Inhibition or Stimulation of the Vertical Growth of the Facial Complex, Its Significance to Treatment.
Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice
aged mouse immunosuppression phospholipase A2 restraint stress specific antibody
2010/11/16
Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis. Although age-related ...
Inhibition of chlamydia trachomatis growth by human interferon-α:mechanisms and synergistic effect with interferon-γ and tumor necrosis factor-α
chlamydia trachomatis growth human interferon-α synergistic effect interferon-γ and tumor necrosis factor-α
2009/3/3
We have evaluated the effect of natural human interferon (IFN)-α on the growth of chlamydia trachomatis in human epithelial cells in vitro and revealed that IFN-α has reduced both growth and infecti...
Inhibition effect of Oncostatin M on metastatic human lung cancer cells 95-D in vitro and on murine melanoma cells B16BL6 in vivo
Oncostatin M metastatic human lung cancer cells 95-D murine melanoma cells B16BL6
2009/3/2
Oncostatin M (OSM) is a multifunctional regulator of cell growth and differentiation. It inhibits the growth of many types of tumor cells, but its role in metastasis is unknown. We studied the human...
Sex steroid inhibition of LH induction of the LH receptor
estrogen testosterone luteinizing hormone receptor testis Leydig cell
2009/2/23
Testosterone and estrogen were tested as possible mediators of the prolactin-dependent LH induction of LH receptors in hypophysectomized adult male rats. Animals were injected s.c. with saline, pr...
Characteristics of prolactin-modulated LH induction of LH/hCG receptors. Transient inhibition of receptor induction following prolactin exposure
LH luteinizing hormone
2009/2/23
The temporal relationship between exposure to prolactin (PRL) and luteinizing hormone (LH) induction of LH receptors was investigated in hypophysectomized adult male rats. Testicular homogenate me...
Inhibition of ornithine decarboxylase activity by follicle stimulating hormone in primary culture of rat Sertoli cells
ornithine decarboxylase follicle stimulating
2009/2/23
The effect of follicle stimulating hormone on the activity of ornithine decarboxylase (ODC) was determined in primary culture of rat Sertoli cells. Three different FSH preparations (NIH oFSH-S-15, S...