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Background: Published reports on the effect of alcohol consumption on bone mineral density (BMD) are inconsistent. Objective: The objective of this study was to examine the relation between alcohol...
Background: An adaptive decrease in energy expenditure (EE) in response to 6 mo of severely restricted energy intake was shown in a classic semistarvation study—the Minnesota experiment. Objective:...
Background: Increasing evidence suggests that glutamine is important for the function of many organ systems and supports the use of glutamine-enriched total parenteral nutrition (TPN) during severe...
Background: Total serum homocysteine (tHcy) has been used as an indicator of intracellular vitamin B-12, vitamin B-6, and folate status in adults, but data for neonates and infants are lacking. Vit...
Fatigue sustained during short-term, highintensity exercise in humans is associated with the inability of skeletal muscle to maintain a high rate of anaerobic ATP production from phosphocreatine hy...
Because elderly adults have distinct metabolic characteristics that alter various nutrient requirements, simple extrapolations of nutrient requirements for younger adults are not warranted. Gastroi...
Background: Elevated fasting homocysteine concentrations are considered a risk factor for vascular disease. Homocysteine, which is produced by the transmethylation of methionine, can be either reme...
Background: Weight gain and loss increases and decreases energy expenditure, respectively, out of proportion to changes in metabolic mass. Objective: We hypothesized that changes in energy expendit...
Pregnancy consists of a series of small, continuous physiologic adjustments that affect the metabolism of all nutrients. The adjustments undoubtedly vary widely from woman to woman depending on her...
This article reviews maternal metabolic strategies for accommodating fetal nutrient requirements in normal pregnancy and in gestational diabetes mellitus (GDM). Pregnancy is characterized by a prog...
The objective of this article was to review existing literature concerning the effects and mechanisms of action of fermented dairy products on serum cholesterol concentrations. Although not without...
We reviewed the evidence from human intervention studies for the health effects of probiotic bacteria, ie, live bacteria that survive passage through the gastrointestinal tract and have beneficial ...
It is important that pharmacy students taking basic courses in pharmacology and toxicology are taught about function, regulation and multiplicity of drug metabolizing enzymes. We have developed an eas...
Knowledge of the cytochrome P450 system is important for the pharmacist because this enzyme participates in a number of drug interactions which may affect therapeutic outcomes and cause drug-induced t...
A flexible strategy for large class instruction in drug metabolism is described, which was derived from the SQ3R (survey, question, read, review, recite) method. Students were asked to prepare and dis...

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