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第十三次整脊分会学术交流大会征文通知
腰椎滑脱症 脊椎手术
2017/1/17
为交流推广中医整脊学新理论、新技术和中医防治脊柱劳损病的经验，提高脊柱劳损病的诊疗水平，由中华中医药学会主办，中华中医药学会整脊分会、贵州省中医药学会整脊专业委员会、北京以宗整脊医学研究院承办的“第十三次整脊分会学术交流大会”拟于2017年6月在贵阳召开。
壳聚糖微球/小牛松质骨支架复合缓释体系的制备及体外生物活性评价
壳聚糖 微球体 药物释放系统 小牛松质骨
2018/12/3
目的：通过乳液交联法合成壳聚糖微球并负载骨形态发生蛋白（bone morphogenetic protein-2，BMP-2），再将其复合于脱细胞基质的小牛松质骨支架，制备壳聚糖微球/小牛松质骨支架复合缓释体系。方法： 使用红外光谱仪、扫描电镜对合成的复合缓释系统进行结构表征和形貌观察，并对微球的包封率和载药量进行检测。用动态浸泡的方法来检测BMP-2的体外释放特征，通过体外检测复合体系的细胞毒性...
人体滑膜关节能够在极高的赫兹接触压力（3-18 MPa）下呈现出较低的摩擦系数（0.001-0.03）。无论是静止还是运动状态，关节界面始终都能够保持超低的摩擦系数，支撑人体正常运动过程。研究表明，包覆在骨关节表面的重要软组织——关节软骨在减小骨与骨之间的摩擦以及缓冲运动时产生的震动等方向起着至关重要的作用。关节软骨具有非常复杂与精细的结构，而这种结构可以被简化成一种双相模型，即关节软骨具有流体相...
目的：建立磁共振（magnetic resonance imaging，MRI）T1加权像（T1-weighted imaging，T1WI）图像中肌肉脂肪化程度的色阶直方图评估法，分析其临床应用价值。方法： 对25例抗肌萎缩蛋白病患者行大腿肌肉MRI检查，分别采取直视分级法和色阶直方图评估法对肌肉脂肪化程度进行评估，比较两种方法的肌肉脂肪化评估结果及其与年龄、肌力的相关性。用组内相关系数检验两种...
骨质疏松是老年人群中最常见的代谢性骨病，据统计，20%的绝经后女性会发生不同程度的骨质疏松［1］。椎体压缩骨折是骨质疏松最常见的合并症之一，是影响老年人生活质量的重要因素。椎体压缩骨折好发于脊柱胸腰段，临床上表现为不同程度的腰背部疼痛，诊断主要依靠脊柱正侧位X线，观察骨折后椎体楔形变现象。
Free 25-hydroxyvitamin D is low in obesity, but there are no adverse associations with bone health
bone density bone turnover half-life obesity vitamin D vitamin D–binding protein
2018/11/30
Background: The mechanism and clinical significance of low circulating 25-hydroxyvitamin D [25(OH)D] in obese people are unknown. Low total 25(OH)D may be due to low vitamin D–binding proteins (DBPs) ...
软骨中硫化氢含量及其对白介素1β诱导的软骨细胞基质金属蛋白酶13表达的抑制作用
硫化氢 骨关节炎 基质金属蛋白酶 软骨疾病
2018/11/29
目的：研究关节液及关节软骨中硫化氢（hydrogen sulfide，H2S）及其合成酶的含量和变化，以及H2S对白介素1β（interlukin-1β，IL-1β）诱导的软骨细胞人基质金属蛋白酶-13（matrix metalloproteinase 13，MMP-13）表达的影响。方法：收集在北京大学第一医院行膝关节手术（关节镜手术或膝关节置换术）患者的关节液及废弃的关节软骨，用亚甲基蓝法检测...
NELL-1: 高效特异的新型生长因子
Nell1蛋白 骨形态发生蛋白质 骨生成 软骨发生
2018/11/30
骨与其他组织的再生往往需要种子细胞、支架材料和相关生长因子三方面的参与，而生长因子作为维持微环境的重要组成部分，对于组织再生起着重要作用［1-2］。人类尼尔样-1型分子（Nel-like molecule-1, NELL-1）基因位于第11号染色体p15.1p15.2，长度约906 kb，包含20个编码外显子。基因编码的分泌蛋白包含810个氨基酸开放阅读框架，其相对分子质量在糖基化之前约为90 ...
Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly
amino acids dietary supplement elderly insulin-like growth factor I fat-free mass relative skeletal muscle mass sarcopenia vitamin D whey protein
2018/11/28
Background: Interventions to attenuate the adverse effects of age-related loss of skeletal muscle and function include increased physical activity and nutritional supplementation.
Moderate weight loss in obese and overweight men preserves bone quality
bone caloric restriction men obesity sex steroids
2018/12/24
Background: Weight loss (WL) negatively affects bone mineral density (BMD) in older populations and has specifically been shown in women.
Nitrate Supplementation Enhances the Contractile Properties of Human Skeletal Muscle
BEETROOT,JUICE FORCE–FREQUENCY,RELATIONSHIP EXCITATION–CONTRACTION,COUPLING MUSCLE,STRENGTH EXPLOSIVE,FORCE,PRODUCTION
2017/5/25
Dietary nitrate supplementation positively affects cardiovascular function at rest and energy metabolism during exercise in humans and has recently also been reported to markedly enhance the in vitro ...
Visceral adiposity is negatively associated with bone density and muscle attenuation
analytic morphomics bone density computed tomography muscle attenuation visceral adiposity
2018/12/20
Background: The storage of adipose tissue in ectopic compartments is a hallmark attribute linking greater body mass index (BMI) with cardiometabolic diseases. Despite ample evidence to confirm that in...
Visceral adiposity is negatively associated with bone density and muscle attenuation
analytic morphomics bone density computed tomography muscle attenuation visceral adiposity
2018/12/20
Background: The storage of adipose tissue in ectopic compartments is a hallmark attribute linking greater body mass index (BMI) with cardiometabolic diseases. Despite ample evidence to confirm that in...
Musculoskeletal Risk Factors as Predictors of Injury in Community-Dwelling Women
PHYSICAL,ACTIVITY,BEHAVIOR HYPERMOBILITY PHYSICAL,ACTIVITY,GUIDELINES STRUCTURAL,FACTORS
2017/5/24
Participating in health-related physical activity (PA) may increase risk for musculoskeletal injury (MSI).
MIT chemical engineers have devised a new implantable tissue scaffold coated with bone growth factors that are released slowly over a few weeks. When applied to bone injuries or defects, this coated s...