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2020年2月10日,中国科学院分子细胞科学卓越创新中心(生物化学与细胞生物学研究所)许琛琦研究员受邀在Nature Metabolism发表了题为“Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities”的综述论文,系统性总结了胆固醇代谢在肿瘤微环境中受到的调控及促进肿瘤发生发展过程的机制,并进一步提出...
近年来,我校生命科学学院林圣彩教授课题组在葡萄糖感知及其对代谢稳态的维持,特别是在对葡萄糖水平的下降并进一步激活代谢的核心调控者AMPK(AMP-activated protein kinase)从而调节下游的代谢通路的机制上,取得了一系列重大进展。2013年,他们发现AXIN蛋白是将上游激酶LKB1带到AMPK并激活它的桥梁(Cell Metabolism,2013)。 2014年,他们的文章解...
2019年4月8日,《Nature Metabolism》以“The long noncoding RNA lnc-ob1 facilitates bone formation by upregulating Osterix in osteoblasts ”(成骨细胞中的lnc-ob1上调Osterix促进骨形成)为题,在线发表了我国科学家在骨质疏松基础研究领域取得的重大科研成果。这是该杂志首次以...
厦门大学医学院生理学课件 Energy metabolism and body temperature。
近日,我校生命科学学院林圣彩教授和林舒勇副教授研究团队在《Cell Metabolism》杂志上在线发表了题为“AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity”的研究论文。该文已于4月3日...
Two experiments were conducted to assess gender (Experiment 1) and age (Experiment 2) effects on the expression of genes related to lipid metabolism in broiler chickens. The expression of fatty acid ...
The human body has two primary kinds of fat—white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered intere...
At a population level, there is growing evidence of the beneficial effects of dietary flavonoids on health. However, there is extensive heterogeneity in the response to increased intake, which is like...
Background: Low potassium has been identified both as a risk factor for type 2 diabetes and as a mediator of the racial disparity in diabetes risk. Low potassium could be a potentially modifiable risk...
Background: Little is known about placental vitamin D metabolism and its impact on maternal circulating vitamin D concentrations in humans.
We are pleased to announce the Cold Spring Harbor Asia conference on Cell Signaling & Metabolism in Development & Disease which will be held in Suzhou, China, located approximately 60 miles west of Sh...
Background: Vitamin B-12 (cobalamin) deficiency may produce severe neurologic and hematologic manifestations. Approximately 20–25% of circulating cobalamin binds to transcobalamin 2 (TCN2), which is r...
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...
Background: Female age-related estrogen deficiency increases the risk of osteoporosis, which can be effectively treated with the use of hormone replacement therapy. However, hormone replacement therap...

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