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Regulation Of The Saccharomyces Cerevisiae INO1 Gene: Novel Insights Into A Hallmark Of Eukaryotic Transcription Regulation
Biological sciences Saccharomyces cerevisiae INO1 Eukaryotic transcription regulation Basic helix loop helix Ino1 Inositol Sna3
2015/1/28
Transcription regulation in eukaryotes is a complex process governed by the concerted action of different factors. The work in this thesis is focused on transcriptional regulation in Saccharomyces cer...
Gene typing of the colonisation factor K88 (F4) in enterotoxigenic Escherichia coli strains isolated from diarrhoeic piglets
K88 F4 PCR colonisation factor
2015/1/20
More than 4 000 E. coli strains isolated from diarrhoeic piglets in 111 pig herds in the Czech Republic during the period 1995–2000 were examined for serogroup and virulence factors. Gene typing of th...
A Phylogenetic Analysis of Armored Scale Insects, Based Upon Nuclear, Mitochondrial, and Endosymbiont Gene Sequences
Diaspididae Coccoidea evolution
2015/1/4
Armored scale insects (Hemiptera: Diaspididae) are among the most invasive insects in the world. They have unusual genetic systems, including diverse types of paternal genome elimination (PGE) and par...
Implementation and scaling of the fully coupled Terrestrial Systems Modeling Platform (TerrSysMP v1.0) in a massively parallel supercomputing environment – a case study on JUQUEEN (IBM Blue Gene/Q)
Terrestrial Systems Modeling Platform Implementation
2014/12/19
Continental-scale hyper-resolution simulations
constitute a grand challenge in characterizing nonlinear feedbacks of states and fluxes of the coupled water, energy, and
biogeochemical cycles o...
Evolution of Hybrid Incompatibilities in Gene Regulatory Networks
antagonistic coevolution cis-trans coevolution compensatory evolution parasitism pleiotropy speciation
2014/12/18
Under the Dobzhansky-Muller model, postzygotic isolation results from incompatibility between interacting genes. Evidence points to regulatory networks as a rich source of incompatibilities that impac...
Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes
NAFLD PNPLA3 fatty liver iver enzymes GDM fatty liver ransaminase ALT trial
2018/12/20
Background: A single nucleotide polymorphism (SNP) of the patatin-like phospholipase-3 (PNPLA3)/adiponutrin gene (rs738409 C>G) is strongly associated with nonalcoholic fatty liver disease; to our kno...
Isoleucine-to-methionine substitution at residue 148 variant of PNPLA3 gene and metabolic outcomes in gestational diabetes
NAFLD PNPLA3 fatty liver liver enzymes GDM fatty liver transaminase ALT trial
2018/12/20
Background: A single nucleotide polymorphism (SNP) of the patatin-like phospholipase-3 (PNPLA3)/adiponutrin gene (rs738409 C>G) is strongly associated with nonalcoholic fatty liver disease; to our kno...
HOUSTON – (Dec. 16, 2014) – Rice University scientists have detected at least three instances of cross-species mating that likely influenced the evolutionary paths of “old world” mice, two in recent t...
Sex Difference in Calbindin Cell Number in the Mouse Preoptic Area: Effects of Neonatal Estradiol and Bax Gene Deletion
Sex Difference Calbindin Cell Number Mouse Preoptic Area Neonatal Estradiol Bax Gene Deletion
2014/12/12
The sexually dimorphic nucleus of the preoptic area (SDN-POA) was first discovered in rats and is one of the most famous and best studied sex differences in the field of neuroscience. Though well docu...
Cloning and characterization of a new gene involved in lymphocyte activation
The immune system mouse models cow in vitro lymphocyte activation immunology lymphocyte activated gene
2014/12/11
Cattle represent an economically important species whose immune system seems to depart from the standard human and murine models. Little has been documented about bovine lymphocyte activation in vitro...
{\it CSE1}, an essential yeast gene required for cell cycle progression, encodes a nuclear transport factor
Brewing yeast genes chromosomes genes cell cycle and protein nuclear proteins
2014/12/11
CSE1, an essential Saccharomyces cerevisiae gene was initially isolated in a screen for genes important for accurate chromosome segregation. cse1 mutants have pleiotropic phenotypes including defects ...
Understanding mitochondrial biogenesis through gene relocation
Yeast the genes oxidative phosphorylation enzymes proteins small ribosomes membrane protein the catalyst
2014/12/11
The yeast mitochondrial genome encodes seven hydrophobic subunits of oxidative phosphorylation enzymes and Var1p, an essential protein in the small ribosomal subunit. Expression of the membrane protei...
Maternal thyroid hormone regulates gene expression in the fetal rat brain
Clinical thyroid hormone the fetus gene
2014/12/11
Recent clinical evidence indicates that thyroid hormone plays an essential role in fetal brain development. However, the mechanism by which thyroid hormone affects development has been largely unexplo...
Characterization and analysis of the cuticlin gene family of the human parasite Onchocerca volvulus
Onchocerciasis silk worm parasites river blindness in Africa plate tail volvulus infectious blindness life cycle the human host bone corneous layer
2014/12/11
Onchocerciasis, or African River blindness caused by the filarial parasite Onchocerca volvulus is the second leading cause of infectious blindness world-wide, with over 18 million people infected. The...
Energy availability signals and the prohormone convertase 1 gene are regulated by Nhlh2
Gene regulation signals transcription factors leptin thalamus arcuate nucleus neurons
2014/12/11
Body weight is controlled by gene regulation through the activation of signal transduction pathways which ultimately regulate transcription factors and their gene targets. Fluctuating leptin levels re...