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Insulin-like growth factor-binding protein-5 (IGFBP-5) is one of the six members of IGFBP family, important for cell growth, apoptosis and other IGF-stimulated signaling pathways. In order to explore ...
The production of therapeutic proteins from transgenic animals is one of the most important successes of animal biotechnology. Milk is presently the most mature system for production of therapeutic pr...
Poultry products are an important source of Salmonella enterica. An effective way to reduce food poisoning due to Salmonella would be to breed chickens more resistant to infection. Unfortunately host ...
To investigate the influence of the prolactin receptor 3 (PRLR3) gene and the retinol-binding protein 4 (RBP4) gene on the production traits of swine, genotyping was performed on 156 and 141 Berkshire...
Interferon regulatory factor 6 (IRF6) gene is a member of the IRF-family, and plays functionally diverse roles in the regulation of the immune system. In this report, the 13,720 bp porcine IRF6 genomi...
The trial was conducted to evaluate the effects of sea buckthorn leaves (SBL) on meat flavor in broilers during heat stress. A total 360 one-day-old Arbor Acre (AA) broilers (male) were randomly allot...
Biochemical reaction networks are subjected to large fluctuations due to small molecule numbers, yet underlie reliable biological functions. Most theoretical approaches describe them as purely determi...
This thesis aims at the logical analysis of discrete processes, in particular of such generated by gene regulatory networks. States, transitions and operators from temporal logics are expressed in the...
Trisomy 21 occurs in approximately 1 out of 750 live births and causes brachycephaly, a small oral cavity, a shortened mid-face, and mental impairments in individuals with Down syndrome (DS). Craniofa...
The plant expression vector pBRSAg was constructed as suitable for transformation via Agrobacteriummediated approach. It contains all elements for plantexpression, such as CaMV 35S promoter, both left...
以甘肃主要推广春小麦品种陇春22幼胚为转基因受体材料,建立了农杆菌介导的小麦遗传转化体系。以预培养4天的幼胚愈伤组织为受体,C58c1农杆菌菌株为供体,将含有半夏凝集素基因的重组质粒pBIpta转入了小麦,经G418 25 mg/L抗性筛选、PCR检测和荧光定量PCR检测共获得转基因植株3株,外源基因的插入拷贝数分别为2、1、3。同时对转基因小麦的T1代植株进行了PCR检测和抗虫性分析,表明半夏凝...
原先存在的基因经过一些改良可能获得新的属性从而承担新的功能. 在分子遗传的层次, 这个过程通常伴随基因重复以及基因重复后旁系同源基因的功能分化. 本研究探索了基因重复后荷尔蒙、受体间特异性相互作用的演化形成. 尽管对这个问题已有相关研究报道,但针对更多个案的研究能帮助我们更好地理解此前已经提出的进化模型的普遍性, 可能还有助于发现新的进化模式. 基于生物信息学的手段, 结合比较基因组学、系统发育学...
Based on the phosphorelay kinetics operative within BvgAS two component system we propose a mathematical model for signal transduction and differential gene regulation in Bordetella pertussis. To unde...
he dawn of the genetic era has allowed for investigation of gene transfer therapy as a treatment for certain diseases. Fanconi anemia (FA) is a rare genetic disorder in which the majority of patients ...
Transcription and alternative splicing play important roles in HIV-1 gene expression and replication and mandate complicated but coordinated interactions between the host and the virus. Studies from o...

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