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MECHANISMS OF VARIABILITY IN CYP2D6 METABOLISM: THE CONTRIBUTIONS OF POLYMORPHISMS, COPY NUMBER VARIATIONS AND microRNA
COPY NUMBER VARIATIONS microRNA
2015/5/21
Cytochrome P450 2D6 (CYP2D6) is an important drug metabolizing enzyme that is involved in the metabolism of 20-25% of commonly prescribed drugs. There is interindividual variability in CYP2D6 enzyme a...
The scaling of X-ray variability with luminosity in Ultra-luminous X-ray sources
Cosmology and Extragalactic Astrophysics (astro-ph.CO)
2011/1/5
We investigated the relationship between the X-ray variability amplitude and X-ray luminosity for a sample of 14 bright Ultra-luminous X-ray sources (ULXs) with XMM-Newton/EPIC data, and compare it wi...
Variability of black-hole accretion discs: a theoretical study
Solar and Stellar Astrophysics (astro-ph.SR) Galaxy Astrophysics (astro-ph.GA)
2010/12/29
This thesis investigates phenomena occurring in black-hole accretion discs which are likely to induce high-frequency quasi-periodic variability. Two classes of pseudo-relativistic theoretical models a...
Testing the No-Hair Theorem with Observations in the Electromagnetic Spectrum. III. Quasi-Periodic Variability
High Energy Astrophysical Phenomena (astro-ph.HE) General Relativity and Quantum Cosmology (gr-qc)
2010/12/24
According to the no-hair theorem, astrophysical black holes are uniquely described by their masses and spins. An observational test of the no-hair theorem can be performed by measuring at least three ...
Phenotypic robustness can increase phenotypic variability after non-genetic perturbations in gene regulatory circuits
Phenotypic robustness increase phenotypic variability non-genetic perturbations gene regulatory circuits
2010/11/15
Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic sta...
Temporal variability of mineral dust concentrations over West Africa: analyses of a pluriannual monitoring from the AMMA Sahelian Dust Transect
Temporal variability mineral dust concentrations West Africa the AMMA Sahelian Dust Transect
2010/10/11
The Sahelian belt is known to be a region where atmospheric levels of suspended mineral dust are among the highest observed on Earth. In the framework of the AMMA (African Monsoon Multidisciplinary An...
Spatially Resolved Images and Solar Irradiance Variability
Solar chromosphere spatially resolved images chromospheric features irradiance variability
2010/9/15
The Sun is the primary source of energy that governs both the terrestrial climate and near-earth space environment. Variations in UV irradiances seen at earth are the sum of global (solar dynamo) to r...
Temperature variability and trends in the UT-LS over a subtropical site: Reunion (20.8° S, 55.5° E)
Temperature variability and trends the UT-LS a subtropical site Reunion (20.8° S, 55.5° E)
2010/9/21
This paper mainly focuses on the trends and variability of the UT-LS temperature using radiosonde observations carried out over 16 years (January 1993 to December 2008) from a southern subtropical sit...
Joint spatial variability of aerosol, clouds and rainfall in the Himalayas from satellite data
aerosol clouds rainfall the Himalayas satellite data
2010/9/21
Satellite-based precipitation, Aerosol Optical Depth (AOD), Cloud Optical Depth (COD), and Aerosol Index (AI) data were used to characterize the linkages among landform and the intra-annual variabilit...
Connecting European snow cover variability with large scale atmospheric patterns
European snow variability with large scale atmospheric patterns
2010/9/10
Winter snowfall and its temporal variability are important factors in the development of water management strategies for snow-dominated regions. For example, mountain regions of Europe rely on snow fo...
Spatial and Temporal Variability of Soil Moisture
Soil Moisture Spatial Temporal Variability, Kriging
2013/3/6
The characterization of temporal and spatial variability of soil moisture is highly relevant for understanding the many hydrological processes, to model the processes better and to apply them to conse...
High variability of the heterogeneous ice nucleation potential of oxalic acid dihydrate and sodium oxalate
the heterogeneous ice nucleation oxalic acid dihydrate sodium oxalate
2010/8/25
The heterogeneous ice nucleation potential of airborne oxalic acid dihydrate and sodium oxalate particles in the deposition and condensation mode has been investigated by controlled expansion cooling ...
Testing seawater Sr isotopic variability on a glacial-interglacial timescale: An application of latest high-precision thermal ionization mass spectrometry
TIMS Sr isotopes seawater glacial-interglacial cycle
2017/8/9
Stability in seawater 87Sr/86Sr ratios over a glacial-interglacial timescale has gained the consensus, yet inter-site inconsistency exists in the previous data employed for validation of this issue. T...
An investigation of the sub-grid variability of trace gases and aerosols for global climate modeling
the sub-grid variability trace gases and aerosols global climate modeling
2010/8/16
One fundamental property and limitation of grid based models is their inability to identify spatial details smaller than the grid cell size. While decades of work have gone into developing sub-grid tr...
Spatial variability and trends of the rain intensity over Greece
Spatial variability trends of the rain intensity
2010/9/10
In this study, the spatial and temporal variability of the mean annual rain intensity in Greece are examined during a 41-year period (1962–2002). The meteorological datasets concern monthly rain amoun...