搜索结果: 1-15 共查到“知识库 核酸生物化学”相关记录324条 . 查询时间(1.109 秒)
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国务院印发新冠病毒抗原检测应用方案
国务院 新冠病毒 抗原检测 隔离治疗
2023/5/26
抗原检测具有感染早期灵敏度高的特点,为指导有需求人员自主、规范做好新冠病毒抗原检测(以下简称抗原检测),现提出以下方案:
国务院联防联控机制印发《新冠肺炎疫情防控核酸检测实施办法》等4个文件
国家卫生健康委员会 新冠肺炎 核酸检测
2023/2/17
为进一步指导各地各部门做好新冠肺炎疫情防控工作,根据《新型冠状病毒肺炎防控方案(第九版)》《关于进一步优化新冠肺炎疫情防控措施科学精准做好防控工作的通知》有关要求,国务院联防联控机制综合组于近日发布《新冠肺炎疫情防控核酸检测实施办法》《新冠肺炎疫情风险区划定及管控方案》《新冠肺炎疫情居家隔离医学观察指南》《新冠肺炎疫情居家健康监测指南》。
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近日,西安交通大学生命学院生命分析化学与仪器研究所赵永席教授团队受邀在国际权威期刊《化学研究评述》(Accounts of Chemical Research)发表题为《DNA编码扩增点亮单细胞核酸修饰》(Lighting up Nucleic Acid Modifications in Single Cells with DNA-Encoded Amplification)的综述论文,系统介绍了...
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核酸检测技术“上新” 较传统方法漏判、误判率更低(图)
核酸检测技术 数字PCR技术 传统方法 病毒携带者
2022/4/13
数字PCR技术灵敏度高、可精准定量。那些多次采用实时荧光定量PCR方式进行核酸检测,结果却为阴性的病毒携带者,利用数字PCR技术就能准确地检测出他们是阳性患者。
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数据说话:7问mRNA新冠疫苗到底行不行?(图)
核糖核酸 新冠疫苗 T细胞 S蛋白
2023/6/14
mRNA,即信使RNA (或信使核糖核酸),是由DNA的一条链作为模板转录而来的、携带遗传信息能指导蛋白质合成的一类单链核糖核酸,利用脂质体将mRNA运输到人类细胞中可以实现诱导蛋白质表达。
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Cas12a属于II类V-A CRISPR系统,它是用CRISPR RNA (crRNAs)编程,通过RuvC结构域特异性识别和切割dsDNA或单链DNA (ssDNA)。Cas12a在识别其目标dsDNA时,可以释放单链脱氧核糖核酸酶(ssDNase)活性,不加区分地切割附近的ssDNA(即反式切割)。基于 CRISPR/Cas12a 系统的传感方法在恒温条件下就可以进行,不需要很高的温度,在一...
《新冠病毒疫苗接种技术指南(第一版)》
北京护理学会 疫苗接种 CHO细胞 新冠病毒疫苗
2023/2/20
目前,我国已有5个生产企业的新冠病毒疫苗批准附条件上市或紧急使用。附条件批准上市的3个灭活疫苗和腺病毒载体疫苗Ⅲ期临床试验期中分析结果显示,疫苗保护效力均达到国家药品监督管理局《新型冠状病毒预防用疫苗临床评价指导原则(试行)》的要求,也符合世界卫生组织《新冠病毒疫苗目标产品特性》推荐的指标要求。临床试验和紧急使用阶段及前期重点人群较大规模接种后疑似预防接种异常反应监测数据表明,新冠病毒疫苗安全性良...
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如何提高新型冠状病毒核酸检测的阳性率(图)
护理教育 核酸检测 肺炎 阳性
2023/4/3
自2019年12月以来湖北武汉陆续发现不明原因肺炎病例,对呼吸道标本病毒基因测序证实病原体为一种新型冠状病毒,世界卫生组织(World Health Organization,WHO)正式将其命名为“2019 新型冠状病毒”(2019 novel coronavirus,2019-nCoV)[1]。截止到2月28日24时全国累计确诊新型冠状病毒肺炎病例66 337例,累计死亡2 727例[2]。如...
新型冠状病毒核酸检测引物和探针序列(Specific primers and probes for detection 2019 novel coronavirus)
新型冠状病 毒核酸检测 探针序列
2023/3/1
新型冠状病毒核酸检测引物和探针序列
Alternative polyadenylation and polymorphisms of 3'untranslated regions of bovine BBOX1 gene
candidate gene transcript variants meat quality carcass traits association analysis
2018/11/23
l-Carnitine, a key element in fatty acid metabolism and energy production, is biosynthesized from gamma-butyro-betaine by the catalysis of gamma-butyrobetaine hydroxylase (BBOX1). We cloned three diff...
Electrostatic and Conformational Effects on the Electronic Structures of Distortional Isomers of a Mixed-Valence Binuclear Cu Complex
Electrostatic Conformational Electronic Structures Distortional Isomers Mixed-Valence Binuclear Cu Complex
2016/5/23
The electronic structure of the binuclear copper complex [Cu(2)(L)](3+) [L = N(CH(2)CH(2)N(H)CH(2)CH(2)N(H)CH(2)CH(2))(3)N] has been investigated by resonance Raman and electroabsorption spectroscopy....
Spatially localized generation of nucleotide sequence-specific DNA damage
sperm chemotaxis fertilization TPX-1 AEG CRISP
2016/5/23
Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate tha...
Hydrogen Bonding Modulates Binding of Exogenous Ligands in a Myoglobin Proximal Cavity Mutant
Alanine Amino Acid Substitution Animals Binding Sites Glycine Histidine Hydrogen Bonding Imidazoles Ligands Macromolecular Substances Metmyoglobin Models, Chemical Mutagenesis, Insertional Myoglobin Nitric Oxide Nuclear Magnetic Resonance,Biomolecular Protons Serine Threonine Whales
2016/5/23
In the sperm whale myoglobin mutant H93G, the proximal histidine is replaced by glycine, leaving a cavity in which exogenous imidazole can bind and ligate the heme iron (Barrick, D. (1994) Biochemistr...
Mg Coordination by Amino Acid Side Chains is Not Required for Assembly and Function of the Special Pair in Bacterial Photosynthetic Reaction Centers
Amino Acids Fourier Analysis Light-Harvesting Protein Complexes Magnesium xidation-Reduction Photosynthetic Reaction Center Complex Proteins Spectrometry,Fluorescence Spectrum Analysis, Raman
2016/5/23
A conserved histidine serves as the axial ligand to the Mg of bacteriochlorophylls in the photosynthetic reaction center (RC) and many other photosynthetic systems. The histidine axial ligands to each...