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Daily supplementation with 15 μg vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial
vitamin D vitamin D2 vitamin D3 25-hydroxyvitamin D randomized controlled trial food fortification healthy women South Asian white European
2018/11/15
Background: There are conflicting views in the literature as to whether vitamin D2 and vitamin D3 are equally effective in increasing and maintaining serum concentrations of 25-hydroxyvitamin D [25(OH...
Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level
Cholecalciferol calcidiol vitamin D3
2016/6/12
The Food and Nutrition Board of the National
Academy of Sciences states that 95 g vitamin D/d is the lowest
observed adverse effect level (LOAEL).
Vitamin D activity of breast milk in women randomly assigned to vitamin D3 supplementation during pregnancy,
breast milk vitamin D 25-hydroxyvitamin D pregnancy supplementation infant feeding
2018/11/27
Background: Human milk is typically low in vitamin D activity (VDA). Whether the vitamin D content of breast milk at birth can be increased by supplementing the mother during pregnancy has not been re...
Effects of vitamin D3 on expression of defensins, Toll-like receptors, and vitamin D receptor in liver, kidney, and spleen of Silky Fowl
vitamin D3 induction chicken avian β-defensins real-time PCR
2015/6/24
The expression of avian β-defensins (AvBDs), Toll-like receptors (TLRs), and vitamin D receptor (VDR) following in vivo vitamin D3 injection was studied. Healthy 90-day Silky Fowls were abdominally in...
Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D3–fortified bread and milk during winter in Denmark
genetic polymorphism SNPs UVB radiation vitamin D status 25-hydroxyvitamin D vitamin D supplements
2018/12/20
Background: Little is known about how the genetic variation in vitamin D modulating genes influences ultraviolet (UV)B–induced 25-hydroxyvitamin D [25(OH)D] concentrations. In the Food with vitamin D ...
Use of Vitamin D3 and Its Metabolites in Broiler Chicken Feed on Performance, Bone Parameters and Meat Quality
Cholecalciferol Meat Quality Bone Strength
2016/5/11
The objective of this experiment was to assess the use of different vitamin D metabolites in the feed of broiler chickens and the effects of the metabolites on performance, bone parameters and meat qu...
Effect of Surfeit Concentrations of Vitamin D3 on Performance,Bone Mineralization and Mineral Retention in Commercial Broiler Chicks
bone mineralization broiler chicks calcium growth phosphorus vitamin D3
2009/7/29
An experiment was conducted to see the effect of higher concentrations of vitamin D3 in diets containing sub optimal levels of calcium (Ca) and non-phytate phosphorus (NPP) in broiler chickens. Maize...
Chemoprevention of MNU and Testosterone induced prostate carcinogenesis by Calcitriol (vitamin D3) in adult male albino Wistar rats
Calcitriol Chemoprevention Methyl nitroso urea Prostate cancer Prostatic intraepithelial neoplasia
2009/7/15
Background Calcitriol is a steroid hormone, inhibits the proliferation and promotes the differentiation of human prostate cancer cells. Calcitriol markedly inhibits the invasiveness of human prostate ...
The skeletal benefits of calcium- and vitamin D3–fortified milk are sustained in older men after withdrawal of supplementation: an 18-mo follow-up study1,2,3
Milk supplementation fortified milk supplement withdrawal men bone mineral density
2009/4/20
Background: In a previous 2-y randomized controlled trial, we showed that calcium- and vitamin D3–fortified milk stopped or slowed bone loss at several clinically relevant skeletal sites in older me...
Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity
vitamin D3 type-1 cellular immunity
2009/3/2
1α,25-dihydroxyvitamin D3 [Calcitriol or 1,25(OH)2D3] is an important active metabolite involved in multiple functions but its calcemic effect in vivo limits its therapeutic applications. On the oth...
A Novel Modulatory Role of Vitamin D3 in Exercise-Induced Apoptosis of Rat Skeletal Muscle
Novel Modulatory Vitamin D3 Apoptosis Rat Skeletal Muscle
2009/1/21
The present study has been designed to investigate the possible modulating role of vitamin D3 on chronic exercise-induced apoptosis in skeletal (gastrocnemius) muscle of rats. Rats were run for 8 week...
Safety of vitamin D3 in adults with multiple sclerosis
Vitamin D safety 25-hydroxyvitamin D 25(OH)D multiple sclerosis
2008/12/17
Background: Vitamin D3 may have therapeutic potential in several diseases, including multiple sclerosis. High doses of vitamin D3 may be required for therapeutic efficacy, and yet tolerability—in the ...
Randomized comparison of the effects of the vitamin D3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients
biochemical responses vitamin D3
2008/4/23
For adults, vitamin D intake of 100 mcg (4000 IU)/day is physiologic and safe. The adequate intake (AI) for older adults is 15 mcg (600 IU)/day, but there has been no report focusing on use of this do...
Relationships of low serum vitamin D3 with anthropometry and markers of the metabolic syndrome and diabetes in overweight and obesity
anthropometry vitamin D3
2008/4/23
Low serum 25 hydroxyvitamin D3 (vitamin D3) is known to perturb cellular function in many tissues, including the endocrine pancreas, which are involved in obesity and type II diabetes mellitus (TIIDM)...