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Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth
developmental programming liver disease coenzyme Q low birth weight accelerated postnatal growth
2018/11/28
Background: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmen...
Caloric Restriction and Formalin-Induced Inflammation:An Experimental Study in Rat Model
Caloric Restriction Inflammation Animal Models Iran
2015/11/9
Background: Acute and chronic inflammations are difficult to control. Using chemical anti-inflammatory medications along with their complications considerably limit their use. According to Traditional...
Impact of cadmium on the level of hepatic metallothioneins, essential elements, and selected enzymes in the experimental rat model
metal intoxication liver blood plasma detoxification Rattus norvegicus L.
2015/7/2
The response of different strains of laboratory rats (Rattus norvegicus L.) on both acute (via intraperitoneal injection) and chronic (via drinking water and/or diet) cadmium intoxication was investig...
Effects of exercise and caffeic acid phenethyl ester after chronic exercise rat model
Caffeic acid phenethyl ester exercise leptin resistin weight control
2015/5/8
In order to understand whether exercise and caffeic acid phenethyl ester (CAPE) has an effect on obesity and weight control, we investigated the effects of CAPE, and exercise on lipid parameters (trig...
Treadmill Exercise Improves Impaired Spatial Memory Function in Partial androgen Deficiency Rat Model
deficiency PADAM testosterone memory
2015/5/7
Elderly men have a relative deficiency of testosterone compared with younger men (i.e., partial androgen deficiency of the aged male (PADAM)). In the cognitive impairment in elderly men, testosterone ...
Immunohistological changes in skin wounds during the early periods of healing in a rat model
tissue repair and regeneration cell differentiation transition proliferation wound healing
2015/4/16
The complexity of the wound healing process, which is still poorly understood, prompted us to perform an immunohistochemical investigation using rat skin as an in vivo model. Fifteen Sprague-Dawley ra...
Effects of extractum cepae, heparin, allantoin gel and silver sulfadiazine on burn wound healing: an experimental study in a rat model
Extractum cepae heparin allantoin silver sulfadiazine burn rat
2015/4/16
These experiments were conducted in order to compare the effects of extractum cepae, heparin, allantoin gel (CTBX) and silver sulfadiazine (SSD) cream on burn wound healing in rats. Thirty six adult, ...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM tension nanoscale
2014/12/4
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM Tension Nanoscale Ultrastructure Modulus
2014/11/6
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Thymoquinone Suppresses Cellular Proliferation, Inhibits VEGF Production and Obstructs Tumor Progression and Invasion in the Rat Model of DMH-Induced Colon Carcinogenesis
Thymoquinone PCNA-LI VEGF Serum Levels
2013/2/19
A myriad of medicinal effects has been attributed to Thymoquinone (TQ), the major biological-active component of Nigella sativa. TQ has been shown to exhibit potent anti-tumor activities. The present ...
Effect of Pentoxifylline Administration on Mast Cell Numbers and Degranulation in a Diabetic and Normoglycemic rat Model Wound Healing
Pentoxifylline Mast cells Diabetes Mellitus Wound Healing
2015/9/28
Background: Wound healing is a complicated and integrated process. Researches in the molecular level on human and animal models have indicated several molecular changes related to the effect of diabet...
Red Deer Antler Extract Accelerates Hair Growth by Stimulating Expression of Insulin-like Growth Factor I in Full-thickness Wound Healing Rat Model
Hair Growth Wound Healing Growth Factors IGF-I Wingless-type MMTV Integration Site Family (Wnt)
2016/5/10
In order to investigate and evaluate the effects of red deer antlers on hair growth in the full-thickness wound healing model, Sprague-Dawley rats were given incision wounds through the full thickness...
Comparison between Fenugreek and Lovastatin in restoration of endothelial function in an experimental old rat model
Fenugreek Endothelial function rat
2009/12/24
The aim of this study was to compare the effectiveness of Fenugreek (Trigonella foenum-graecum) with that of lovastatin in restoration of endothelia function in the aorta taken form aged N-Mair rats. ...
Effect of dimethyl sulfoxide on injuries and neurological deficits:a rat model of transient focal cerebral ischemia
Dimethyl sulfoxide cerebral ischemia transient focal rat
2009/12/11
Background: Dimethyl sulfoxide (DMSO) has been used as a solvent for many drugs in ischemic experiments. DMSO has many biological benefits, including antioxidant, anti-inflammatory, platelet aggregati...
Effect of dimethyl sulfoxide on injuries and neurological deficits:a rat model of transient focal cerebral ischemia
Dimethyl sulfoxide cerebral ischemia transient focal rat
2009/12/11
Background: Dimethyl sulfoxide (DMSO) has been used as a solvent for many drugs in ischemic experiments. DMSO has many biological benefits, including antioxidant, anti-inflammatory, platelet aggregati...