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Higher serum phenylalanine concentration is associated with more rapid telomere shortening in men
aging amino acids telomeres phenylalanine telomere shortening longitudinal study
2018/11/12
Background: Telomere length and telomere shortening are associated with age-related health outcomes. Only a few studies have been able to longitudinally report on factors that are associated with chan...
Total sulfur amino acid requirement in young men as determined by indicator amino acid oxidation with L-[1-13C]phenylalanine
amino acid requirement stable isotopes phenylalanine
2016/6/14
Determining the sulfur amino acid (SAA) requirements
of humans has remained elusive because of the complex
nature of SAA metabolism. Current recommendations are based
on nitrogen balance studies.
Intake of major nutrients by women in the Maternal Phenylketonuria (MPKU) Study and effects on plasma phenylalanine concentrations
genotype plasma phenylalanine protein
2016/6/13
Women with untreated phenylketonuria (PKU)
often have poor reproductive outcomes.
Tyrosine requirement of healthy men receiving a fixed phenylalanine intake determined by using indicator amino acid oxidation
stable isotopes adult amino acid requirements Amino acid metabolism
2016/6/12
The currently accepted total aromatic amino acid
requirement for adults is based on nitrogen balance measurements
in individuals who received their intake of aromatic amino
acids solely as phenylal...
Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets
Phenylketonuria PKU tyrosine
2016/6/12
Treatment of phenylketonuria (PKU) consists
of restriction of natural protein and provision of a protein substitute
that lacks phenylalanine but is enriched in tyrosine. Large
and unexplained diffe...
Changes in phenols composition and activity of phenylalanine-ammonia lyase in apples after fungal infections
apples postharvest rot fungal pathogens
2015/3/4
Th e defensive reaction of apple cultivar Idared (Malus domestica Borkh.) was studied after inoculation with three diff erent pathogens (Penicillium expansum, Monilinia fructigena, and Gloeospor...
Variability of PSPAL1 (phenylalanine ammonia-lyase gene-1) proximal promoter sequence and expression in pea challenged with Mycosphaerella pinodes
expression Mycosphaerella pinodes phenylalanine ammonia-lyase gene-1 Pisum sativum polymorphism resistance
2014/7/9
Part of the PSPAL1 gene (corresponding to the proximal promoter, exon 1 and intron) from eight pea varieties was sequenced and compared to the published sequence of PSPAL1 gene from Midoriusui cultiva...
Effect of Enzyme Type, Enzyme Substrate Ratio and Temperature on Phenylalanine Removal from Milk
Effect of Enzyme Type Enzyme Substrate Ratio
2016/6/1
Phenylketonuria (PKU) is a metabolic disease in which the untreated patients can show irreversible mental retardation and the use of milk by phenylketonurics patients is forbidden. With the aim of pre...
Comparison of Growth Performance and Whole-body Amino Acid Composition in Red Seabream (Pagrus major) Fed Free or Dipeptide Form of Phenylalanine
Pagrus major Phenylalanine Dipeptide Amino Acid Requirement
2016/5/10
This study was conducted to evaluate the efficacy of the dipeptide form of phenylalanine as a new source of amino acid in terms of growth performance and whole-body amino acid composition in compariso...
Effects of Cold Acclimation on Pythium Snow Rot Resistance, Phenylalanine Ammonia-lyase Activity, and Contents of Phenol, Lignin and Sugar in Barley Leaves
Barley Cell wall Cold acclimation Lignin Phenol Phenylalanine ammonia-lyase
2009/7/7
We studied the relationship between the increase in resistance to Pythium snow rot provided by cold acclimation and changes in phenylalanine ammonia-lyase (PAL) activity, and the contents of total ph...
Preparation of Low-phenylalanine Whey Hydrolysates, Using Papain and Pancreatin Immobilized on Activated Carbon and Alumina
Whey enzymatic immobilization activated carbon alumina enzymatic hydrolyze phenylalanine removal
2008/11/1
This study involves the preparation of whey hydrolysates with low phenylalanine (Phe) content aiming the treatment of phenylketonuria. For hydrolysing the proteins, two enzymes were used, papain and p...
Effect of Adsorption Medium, Hydrolytic Parameters and Ultrafiltration on the Phenylalanine Removal from Pancreatic Whey Hydrolysates
Whey activated carbon amberlite XAD-4 pancreatin protein hydrolysis ultrafiltration
2008/10/26
With the aim of producing dietary supplements for phenylketonurics, using whey hydrolysates as protein sources, the effect of some procedures over phenylalanine (Phe) removal was evaluated. Twelve whe...
Isolation and functional characterization of two rapeseed genes orthologous to Arabidopsis thaliana Phenylalanine Ammonia-lyase 2
Arabidopsis thaliana Brassica napus L ortholog phenylalanine ammonia-lyase (PAL) yellow seed
2010/1/11
Two rapeseed (Brassica napus L.) phenylalanine ammonia-lyase 2 genes (BnPAL2-1 and BnPAL2-2) were isolated. The full-length cDNAs of BnPAL2-1 and BnPAL2-2 are 2422 bp and 2421 bp, with corresponding g...
Vascular Sources of Phenylalanine, Tyrosine, Lysine, and Methionine for Casein Synthesis in Lactating Goats
mammary gland peptides casein synthesis
2008/6/19
The contribution to casein biosynthesis of peptides derived from blood was examined in late lactation goats (254 to 295 d in milk). Ratios of mammary uptake of free amino acids (AA) in blood to output...
苯丙氨酸羟化酶（PAH）基因外显子7及其两侧内含子的突变研究Mutations in Exon 7 of the Phenylalanine Hydroxylase（PAH）Gene in Chinese Patients with Phenylketonuria
苯丙氨酸羟化酶 外显子 基因突变 单链构象多态性 序列分析
2008/1/6
为探讨中国苯丙酮尿症（PKU）人群中苯丙氨酸羟化酶（PAH）基因外显子7的突变特征，对147例PKU患儿的294个PAH基因外显子7以及两侧部分内含子序列，应用PCR－单链构象多态性（SSCP）分析及基因序列分析的方法进行了筛查和确定。共发现13种突变基因：G239D、R241C、R241fs、R243Q、G247S、G247V、R252Q、L255S、R261Q、M276K、E280G、P281...