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南京农业大学农学院《New Phytologist》发表张文利课题组“R‐loops act as regulatory switches modulating transcription of COLD‐responsive genes in rice”（图）
张文利 气候变化 分子机制 作物生长
2023/10/28
随着全球气候变化的不断加剧，低温冻害和冷害已经成为影响农作物生长的一个重要自然胁迫因素。冷胁迫通常影响农作物正常的生长发育进程，严重时导致减产甚至颗粒无收。因此，作物冷应答分子机制研究可为作物耐冷分子育种提供理论参考。植物R-loop在不同的细胞活动中发挥重要作用，包括发育调控和胁迫应答等。然而，在低温敏感型作物如水稻中，R-loop介导冷胁迫应答的分子机制仍鲜有报道。
中国科学院瘤内基因编辑增效ACT疗法研究获进展（图）
瘤内基因 编辑增效 ACT疗法
2023/5/18
过继T细胞转移（adoptive T-cell transfer，ACT）疗法是颇具前景的肿瘤免疫疗法，但对实体瘤效果欠佳，亟需通过学科交叉来发展针对实体瘤增效的新理念和新技术。近日，中国科学院过程工程研究所生化工程国家重点实验室研究员魏炜团队与浙江大学药学院教授平渊团队交叉合作，通过非侵入手段激活实体瘤的基因编辑，同时调控实体瘤物理和免疫微环境，显著提升了多种ACT疗法对实体瘤的疗效。相关研究成...
中国科学院过程工程研究所在瘤内基因编辑增效ACT疗法研究方面取得新进展（图）
瘤内 基因编辑 增效ACT疗法
2023/5/19
过继T细胞转移（adoptive T-cell transfer，ACT）疗法是极具前景的肿瘤免疫疗法，但对实体瘤效果欠佳，亟需通过学科交叉来发展针对实体瘤增效的新理念和新技术。近日，过程工程所生化工程国家重点实验室与浙江大学药学院交叉合作，通过非侵入手段激活实体瘤的基因编辑，并同时调控实体瘤物理和免疫微环境，显著提升了多种ACT疗法对实体瘤的疗效。相关工作发表于Nature Nanotechno...
中国科学院过程工程所在瘤内基因编辑增效ACT疗法研究方面取得新进展（图）
基因编辑 纳米器件 肿瘤细胞
2023/8/16
过继T细胞转移（adoptive T-cell transfer，ACT）疗法是极具前景的肿瘤免疫疗法，但对实体瘤效果欠佳，亟需通过学科交叉来发展针对实体瘤增效的新理念和新技术。2023年5月16日，过程工程所生化工程国家重点实验室与浙江大学药学院交叉合作，通过非侵入手段激活实体瘤的基因编辑，并同时调控实体瘤物理和免疫微环境，显著提升了多种ACT疗法对实体瘤的疗效。相关工作发表于Nature Na...
The Accelerating Deployment of Versatile, Advanced Nuclear for Clean Energy (ADVANCE) Act of 2023, introduced to the US Senate by a bipartisan group, aims to support efforts to develop and deploy new ...
Podcast: Gender balance in nuclear, and the EU's Net Zero Industry Act
核能领域 净零排放法案 Gender balance
2023/4/6
An international survey has highlighted the need for a better gender balance in the nuclear sector, but how to achieve it? That's one of the issues discussed with Corhyn Parr, CEO of Nuclear Waste Ser...
The European Commission (EC) has proposed the Net-Zero Industry Act (NZIA) to scale up manufacturing of clean technologies in the EU and make sure it is well-equipped for the clean-energy transition. ...
Genomic data 'catch corals in the act' of speciation and adaptation（图）
Genomic data catch corals act speciation adaptation
2020/11/13
A U.S. National Science Foundation-funded study led by University of Hawai‘i at Mānoa researchers has revealed that diversity in Hawaiian corals is likely driven by co-evolution among t...
目的 基于斑马鱼代谢-效/毒（M-Act/Tox）联合评价箭叶淫羊藿代谢、抗骨质疏松效应及毒性。方法 用受精后1~6 d（1~6 dpf）斑马鱼评价箭叶淫羊藿（生药质量浓度200、500、1 000、1 500、2 000 μg/mL）的安全性，观察鱼脏器形态、计数死亡数并计算斑马鱼半数死亡浓度（LC50）；用5 dpf斑马鱼暴露于箭叶淫羊藿（生药250 μg/mL）24 h，分析6个代表性黄酮成...
Plants Under Heat Stress Must Act Surprisingly Quickly to Survive（图）
Plants Under Heat Stress Quickly to Survive
2017/9/5
In new results reported in The Plant Cell, molecular biologist Elizabeth Vierling at the University of Massachusetts Amherst and colleagues in India and China report finding a crucial mechanism that p...
Young Stellar System Caught in Act of Forming Close Multiples
Young Stellar System Caught Forming Close Multiples
2016/11/4
For the first time, astronomers have seen a dusty disk of material around a young star fragmenting into a multiple-star system. Scientists had suspected such a process, caused by gravitational instabi...
Skinny lines of ants snake through the rainforest carrying leaves and flowers above their heads—fertilizer for industrial-scale, underground fungus farms. Soon after the dinosaur extinctions 60 millio...
Ethanol Extracts from Mistletoe (Viscum album L.) Act as Natural Antioxidants and Antimicrobial Agents in Uncooked Pork Patties during Refrigerated Storage
Mistletoe Extract Antioxidant Lipid Oxidation Microbial Counts Uncooked Pork Patties
2016/5/20
The antioxidant potential of mistletoe (Viscum album L. var. coloratum Ohwi; VAL) extract in uncooked pork patties was evaluated. Three concentrations of VAL extract (0.1 [T1], 0.5% [T2] and 1.0% [T3]...
The Effect of the Balanced Budget Act of 1997 on Medicare HMO Enrollment
Balanced Budget Act Medicare HMO Enrollment
2016/3/18
Congress implemented a number of measures in the Balanced Budget Act of 1997 (BBA) to encourage Health Maintenance Organizations (HMOs) to enter underserved markets and expand enrollment in existing m...
Conversation Electrified: ERP Correlates of Speech Act Recognition in Underspecified Utterances
Speech Act Recognition Underspecified Utterances
2015/12/18
The ability to recognize speech acts (verbal actions) in conversation is critical for everyday
interaction. However, utterances are often underspecified for the speech act they perform,
requiring li...