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目的：观察老年人睾丸间质细胞结构以及类固醇激素合成快速调节蛋白（steroidogenic acute regulatory protein，StAR）和胆固醇侧链裂解酶（cholesterol-side-chain cleavage enzyme，P450scc）蛋白表达的变化，以探讨迟发性性腺功能减退症的机制。方法：青年人（20~30岁）及老年人（70~90岁）睾丸标本各10例，对患者进行AM...
Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side-Chain Cleavage Enzyme（P450scc）During Leydig Cell Aging
Leydig cell cyclic AMP steroidogenesis Brown Norway rat
2008/12/22
Previous studies have shown that the capacity of Leydig cells from aged (21-24-month-old) Brown Norway rats to produce testosterone is reduced from young (4-month-old) levels, and that this is cor...