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Differential Expression of PPARγ, FASN, and ACADM Genes in Various Adipose Tissues and Longissimus dorsi Muscle from Yanbian Yellow Cattle and Yan Yellow Cattle
PPARγ FASN ACADM Fat Deposition Cattle qRT-PCR
2016/5/16
The objective of this study was to investigate the correlation between cattle breeds and deposit of adipose tissues in different positions and the gene expressions of peroxisome proliferator-activated...
The association of CAPN1, CAST, SCD, and FASN polymorphisms with beef quality traits in commercial crossbred cattle in the Czech Republic
candidate genes tenderness fatty acids composition
2015/6/24
Genetic variability of four polymorphisms (CAPN1, CAST, SCD, and FASN) was evaluated and the relationships between them and the beef quality traits (tenderness and fatty acid composition) in Czech cro...
Developmental patterns of FASN and LIPE mRNA expression in adipose tissue of growing Jinhua and Landrace gilts
gilt carcass fat content FASN LIPE gene expression RT-PCR
2015/6/8
The present study was aimed to investigate the developmental patterns of FASN (fatty acid synthase) and LIPE (lipase, hormone-sensitive) mRNA in adipose tissue in pigs of different breeds and the rela...
探讨脂肪酸合成酶(FASN)在直肠癌患者外周血中的表达变化及意义。 方法:选取经病理活检诊断为直肠癌的患者42例,其中28例行直肠癌根治术(根治组),14例行直肠癌姑息术(姑息组),选取正常人16例(对照组);分别应用ELISA方法检测正常人及直肠癌患者手术前后外周血中FASN的浓度。 结果:术前直肠癌患者外周血FASN水平明显高于对照组(P<0.05);根治组术后患者血FASN低于术前(P<0....
山羊脂肪酸合酶基因(FASN)启动子结构与功能的初步分析
山羊 脂肪酸合酶 启动子 山羊乳腺上皮细胞
2013/12/2
本研究旨在对山羊脂肪酸合酶基因(Fatty acid synthase, FASN)启动子进行结构与功能的初步分析,进而对其转录调控机制进行探讨。采用PCR技术从西农萨能羊基因组DNA中克隆FASN基因启动子,通过缺失分析,构建7个包含不同缺失片段的荧光素酶报告基因载体,转染山羊乳腺上皮细胞和MCF7细胞,利用双荧光素酶系统检测不同片段的启动活性。结果表明,克隆得到FASN基因的启动调控序列2 ...
山羊脂肪酸合酶基因(FASN)启动子结构与功能的初步分析
山羊 脂肪酸合酶 启动子 山羊乳腺上皮细胞
2012/3/21
本研究旨在对山羊脂肪酸合酶基因(Fatty acid synthase, FASN)启动子进行结构与功能的初步分析,进而对其转录调控机制进行探讨。采用PCR技术从西农萨能羊基因组DNA中克隆FASN基因启动子,通过缺失分析,构建7个包含不同缺失片段的荧光素酶报告基因载体,转染山羊乳腺上皮细胞和MCF7细胞,利用双荧光素酶系统检测不同片段的启动活性。结果表明,克隆得到FASN基因的启动调控序列2 ...
脂肪酸合成酶基因(FASN)的研究进展
FASN 基因 多态性 生产性状
2009/6/8
在哺乳动物中, 脂肪酸合成酶在脂肪酸合成中起着至关重要的作用。它含有7 个活性位点, 在还原型辅酶Ⅱ的存在下,FASN 负责
乙酰辅酶A( acetyl- CoA) 和丙二酰辅酶A( malonyl- CoA) 从头合成一种长链软脂酸( 棕榈酸酯) 的所有催化步骤。脂肪酸合成酶是脂肪合成的关键酶, 并且在腹脂肪组织重变异及相关性状变异中起着重要作用。综述了FASN 及其基因在生命活动中的地位、...
DNA Polymorphisms in SREBF1 and FASN Genes Affect Fatty Acid Composition in Korean Cattle (Hanwoo)
SREBF1 FASN Fatty Acid Polymorphism Gene Expression Hanwoo
2016/4/29
Sterol regulatory element binding factor 1 (SREBF1) and fatty acid synthase (FASN) genes play an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. This study ...
研究了脂肪酸合成酶 (Fatty acid synthase, FASN )基因最后1个内含子2个突变的多样性,并运用资源参考家系研究了这2个突变对鸡体重、脂肪沉积性状的影响,结果表明:(1) 红色原鸡Hae ⅢPCRRFLP位点B基因频率为最高(0.85), 泰和鸡及余干乌黑鸡为最低(0.21),品种间差异较大,但未发现肉用与蛋用鸡种间的差异;在Pst I-PCR-RFLP位点上, A基因频...