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以斑马鱼(Danio rerio)为试验生物,经淋巴细胞体外暴露试验,从细胞内源性凋亡角度,研究了饮用水消毒副产物-碘代乙酸诱导斑马鱼淋巴细胞损伤的致毒机理.结果表明,在碘代乙酸的环境浓度1μg·L-1下暴露24、36、48和96 h后,细胞凋亡率从对照组的3.52%分别增加到15.89%、22.47%、40.76%和52.13%,与对照组差异均为极显著(p<0.01);线粒体膜电位分别较对照组下...
Differential Gene Expression in Zebrafish (Danio rerio) Following Exposure to Gaseous Diffusion Plant Effluent and Effluent Receiving Stream Water
Zebrafish gene expression metals ethoxyresorufin-o-deethylase
2010/12/22
Transcription of the biomarker enzyme cytochrome P4501A1 (CYP1A1) was significantly elevated in fish exposed to one plant effluent at both the 7 (16 fold) and 14 (10 fold) day time points. Sediment PC...