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Effects of a bilberry preparation on selected cell lines of the digestive system
Vaccinium myrtillus L. cytotoxicity functional food genotoxicity mutagenicity
2016/12/9
Bilberry is a valuable wild forest fruit harvested in many countries in Europe. The biological activities of bilberry include antioxidant, anticancer, antiviral, antibacterial, and anticholinesterase ...
Effects of curcumin in combination with cyclophosphamide on canine mammary tumour cell lines
curcumin cyclophosphamide apoptosis combination index canine mammary cancer
2015/4/17
In recent years, significant emphasis has been placed on combination chemotherapy in cancer using cytotoxic agents and plant derived-bioactive substances that are capable of selectively arresting cell...
Effects of Phytochemicals from Rhodiola crenulata on Highly Invasive Breast Cancer Cell Lines and Embryonic Models of Migration
Cancer Mammary Metabolism Metastasis Natural Product Rhodiola crenulata
2014/12/10
The root of the Tibetan plant Rhodiola crenulata is part of eastern traditional medicine. Studies have suggested that members of the Rhodiola genus display anticancer properties. In this study we exam...
Construction of Recombinant Bacmid Containing M2e-Ctxb and Producing the Fusion Protein in Insect Cell Lines
Influenza Vaccines Baculovirus Cholera Toxin Subunit B
2015/10/10
Background:: Sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. Ectodomain of influenza M2 protein is a surface and highly conserved prot...
In Vitro Characterization of Docetaxel as a Radiosensitizer in Canine and Feline Cancer Cell Lines
Docetaxel Chemotherapy Radiation Therapy In Vitro
2013/2/19
An In Vitro study was conducted to investigate docetaxel as a radiation sensitizer in four canine (mammary carcinoma—CMT12 and CMT25, osteosarcoma—OS2.4, and transitional cell carcinoma—PTCC), and one...
Effects of aqueous garlic extract on oxidant/antioxidant status in 32D and 32Dp210 cell lines
Garlic mouse myeloid cell line oxidant/antioxidant status
2010/12/21
To investigate the possible effects of aqueous garlic extract on the oxidant/antioxidant status and apoptosis in 32D (wild type mouse myeloid cell = normal) and 32Dp210 (BCR-ABL fusion gene (+) mouse ...
Effects of aqueous garlic extract on oxidant/antioxidant status in 32D and 32Dp210 cell lines
Garlic mouse myeloid cell line oxidant/antioxidant status
2010/11/22
To investigate the possible effects of aqueous garlic extract on the oxidant/antioxidant status and apoptosis in 32D (wild type mouse myeloid cell = normal) and 32Dp210 (BCR-ABL fusion gene (+) mouse ...
Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology
Microarrays, reproducibility forensic bioinformatics
2010/10/19
High-throughput biological assays such as microarrays let us ask very detailed questions about how diseases operate, and promise to let us personalize therapy. Data processing, however, is often not d...
Apoptosis Induced by N-Nitrosamines in Two Cancer Cell Lines
N-nitrosopyrrolidine N-nitrosodimethylamine Apoptosis Caspases HL-60 Cells HepG2 Cells
2013/3/13
In the present study, we investigated the induction of apoptosis by N-nitrosopyrrolidine (NPYR) and N-nitrosodimethy-lamine (NDMA) in two human cell lines: HL-60 (leukemia) and HepG2 (hepatoma). Apopt...
Screening of prognostic factors using multiplex RT-PCR technique on different leukemic cell lines
Multiplex RT-PCR T-ALL oncogene leukemia cell
2009/12/18
Background: Leukemia is one of the most common pediatric malignancies. T-cell Acute Lymphoblastic Leukemia (T-ALL) accounts for 15% of hematopoetic cancers. It has been well understood that identifica...
Antitumor Effects of TNF-b,5-FU and Their Combinations on Cervical Carcinoma Cell Lines
TNF-b 5-FU ME180 HeLa Cervical Carcinoma
2009/6/26
Cervical carcinoma is one type of cancer with a high mortality rate in females. In this study, we investigated the cytotoxic effects of TNF-b, 5-FU and their combinations on human cervical carcinoma c...
Are Lymphoblastoid Cell Lines Suitable to Study Increased SMN Gene Expression by Histone Deacetylase Inhibitors?
Spinal muscular atrophy survival motor neuron gene histone deacetylase inhibitors treatment
2009/6/16
Aim: In this preliminary study, we aimed to analyze the effect of sodium butyrate (NB) and phenylbutyrate (PB), belonging to the class of histone deacetylase (HDAC) inhibitors, on lymphoblastoid cell ...
Effects of Fucoidan from Mozuku on Human Stomach Cell Lines
fucoidan Mozuku Cladosiphon okamuranus
2009/5/31
Cladosiphon okamuranus (Okinawamozuku) is a species of Mozuku known to contain the most fucoidan of any brown algae. Fucoidan is a sulfated hetero polysaccharide with various biological activities. We...
Construction of HeLa cell lines overexpressing metallothioneins-1 and -2 and their cytoprotective effects against oxidative damage induced by hydrogen peroxide
cell viability copper cytoprotective effect HeLa cell metallothionein
2009/4/1
It has been suggested that metallothioneins (MTs) play a role to protect cells from toxic effects of oxidative stress and heavy metals. On the other hand, the ability of Cu-containing MT to protect ce...
Antitumor effects of a combination of interferon-alpha and sorafenib on human renal carcinoma cell lines
interferon-alpha sorafenib human renal carcinoma cell lines
2009/3/2
To support the role of interferon (IFN)-α and sorafenib combination therapy against renal cell carcinoma (RCC), the effects of IFN-α and sorafenib on tumor growth, vascular endothelial growth factor...