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一种抗人PrPC蛋白的单克隆抗体,能够以靶向方式降低转录因子Twist1的表达水平,并诱导巨噬细胞和NK细胞靶向直肠癌肿瘤细胞。 抗体与西妥昔单抗联合用药的抑瘤效果也优于单用抗体或西妥昔单抗。
Anew genetic variant that protects against Alzheimer’s disease has been identified by an international team led by Harvard Medical School investigators at Massachusetts General Hospital and Massachuse...
Cancer drugs that stimulate the body’s immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delive...
What does nuclear and radiation have to do in the fight against cancer? In this episode, experts explain the key role of radiation-based technologies in comprehensive cancer control.
In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to rep...
People who share a political ideology have more similar ‘neural fingerprints’ of political words and process new information in similar ways, according to a new analysis led by Brown University resear...
An LHC quadrupole whose beam screen had been coated with a fine layer of carbon displayed minimal heat load in comparison to other magnets, constituting a promising step in eliminating electron clouds...
Like a microscopic bucket brigrade, an artificial microtubule can rapidly transport tiny particles along magnetic stepping stones, delivering them to a precise location even when operating against a s...
Colonoscopy is an important weapon in the fight against colon cancer, which killed 51,000 Americans in 2019, making it the nation’s second-deadliest cancer. But doctors’ ability to catch polyps on the...
Intense blooms of toxic algae are becoming common occurrences along the coast of Florida and elsewhere. Results from a new study found that wearing the face mask everyone has become accustomed to duri...
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
Climate change will shape the future of coastal communities, with flood walls, elevated structures and possibly even floating cities used to combat sea level rise. New research has found that managed ...
One of the biggest unknowns about the coronavirus is how changing seasons will affect its spread. Now physicists at the University of Utah have received a National Science Foundation...
The ISO standardisation of `Testing methods for the mitigation of non-invasive attack classes against cryptographic modules' (ISO/IEC 17825:2016) specifies the use of the Test Vector Leakage Assessmen...
We study the security of symmetric primitives against key-correlated attacks (KCA), whereby an adversary can arbitrarily correlate keys, messages, and ciphertexts. Security against KCA is required whe...

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