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Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
SARS-CoV-2 human ACE2 transgenic mouse COVID-19 pneumonia
2020/6/11
COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human angi...
Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin,muscle,and lymphoid development
Arginine arginase I Peyer’s patch myocyte hair immunonutrition enterocytes transgenic mice
2016/12/19
Background: Arginine is required for the detoxification of ammonia and the synthesis of proteins, nitric oxide, agmatine, creatine, and polyamines, and it may promote lymphocyte function. In suck...