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Development of transmembrane signaling in the fetal rat Leydig cell
transmembrane signaling fetal rat Leydig cell
2009/2/23
Gonadotropin binding to the adult Leydig cell activates a GTP binding protein that interacts with adenylate cyclase to increase cAMP production within the cell. The increased production of cAMP stim...
Stimulation of the proliferation and differentiation of Leydig cell precursors after the destruction of existing Leydig cells with ethane dimethyl sulphonate（EDS）can take place in the absence of LH
proliferation differentiation Leydig cell precursors
2009/2/23
In hypophysectomized rats, 2 days after the administration of the cytotoxic drug ethane dimethyl sulphonate (EDS), the proliferative activity of Leydig cell precursors increased six-fold. Thus, fact...
Mechanism of LHRH-stimulated steroidogenesis in rat Leydig cells：lipoxygenase products of arachidonic acid may not be involved
LHRH-stimulated steroidogenesis rat Leydig cells lipoxygenase products arachidonic acid
2009/2/23
Luteinizing hormone releasing hormone agonist, [(imBzl)-DHis6,Pro9,NEt]-LHRH (LHRH-A), caused a two to threefold increase in in vitro testosterone (T) secretion by rat Leydig cells. This LHRH-A-indu...
Leydig cell and extracellular matrix effects on Sertoli cell function：biochemical and morphologic studies
Leydig cell extracellular matrix Sertoli cell function
2009/2/23
The reciprocal influence between Leydig and Sertoli cells prepared from pig testis were studied by coculture of both types of cells in either plastic dishes or dishes coated with basement membrane...
Transplantation of newborn rat testis under the kidney capsule of adult host as a model to study the structure and function of Leydig cells
newborn rat testis kidney capsule adult host Leydig cells
2009/2/23
Newborn rat testis was transplanted under the kidney capsule of adult castrated and uncastrated male rats to develop and characterize a model system for studies on Leydig cell development. Two weeks...
The actions of calcitonin on the TM3 Leydig cell line and on rat Leydig cell-enriched cultures
calcitonin TM3 Leydig cell line rat Leydig cell-enriched cultures
2009/2/23
Studies demonstrating calcitonin receptors on Leydig cells have suggested that these cells may be one of the many sites affected by this peptide. To investigate this possibility, the effect of syn...
It has been reported that Leydig cells have Fc receptors, which traditionally have been considered markers specific for macrophages and polymorphonuclear leukocytes. The purpose of this investigat...
The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment
Leydig cell Leydig cell precursor LH hCG EDS proliferation
2009/2/23
The proliferation and differentiation of possible Leydig cell precursors in adult rats were studied after destruction of the existing Leydig cells with EDS or after daily treatment with hCG. After 2...
Origin and fate of autophagosomes in Leydig cells of normal adult rats
Origin fate autophagosomes Leydig cells normal adult rats
2009/2/23
Autophagosomes were observed frequently in electron microscope photographs of Leydig cells from normal adult rat testis. Their formation, evolution and fate were analyzed morphologically in preparat...
Binding and internalization in vivo of [125I]hCG in Leydig cells of the rat
Binding and internalization [125I]hCG Leydig cells rat
2009/2/23
The present study was performed to demonstrate the binding, mode of uptake, pathway and fate of iodinated human chorionic gonadotropin ([125I]hCG) by Leydig cells in vivo using electron microscope...
Uptake and release of ascorbic acid by rat Leydig cells in vitro
ascorbic acid rat Leydig cells
2009/2/23
The mechanism by which ascorbic acid is transported into rat Leydig cells in vitro was investigated. Transport of [14C]ascorbic acid was temperature-dependent and inhibited in the absence of sodium ...
Variation in the effect of a nongonadotropic Leydig cell stimulating factor in testicular interstitial fluid after exposure of the testis to a single episode of heat treatment
Variation nongonadotropic Leydig cell testicular interstitial fluid testis
2009/2/23
The activity of a nongonadotropic factor present in rat testicular interstitial fluid and capable of stimulating Leydig cell testosterone production was measured at intervals for 8 weeks after exp...
Follicle stimulating hormone, luteinizing hormone and testicular Leydig cell responses to estradiol immunization in Ile-de-France rams
Follicle stimulating hormone luteinizing hormone testicular Leydig cell estradiol immunization Ile-de-France rams
2009/2/23
Active immunization of Ile-de-France rams against estradiol (E2) resulted in the production of E2-neutralizing antibodies and an elevation in the plasma concentrations of FSH, LH, and testosterone...
The effect of selective destruction and regeneration of rat Leydig cells on the intratesticular distribution of testosterone and morphology of the seminiferous epithelium
selective destruction regeneration rat Leydig cells intratesticular distribution
2009/2/23
This study was designed to explore the relationship between the intratesticular distribution of testosterone and spermatogenesis by completely destroying the Leydig cells of mature male rats with in...
Impaired estrogen production by Leydig cells of the naturally retained testis in unilaterally cryptorchid boars and stallions
testis cryptorchid boar stallion estrogens
2009/2/23
Estrogen production in vitro was compared for Leydig cells from cryptorchid and scrotal testes in boars and stallions. Animals with natural and experimental cryptorchidism were used. Purified Leydig...