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2022年3月28日，杭州医学院药学院梁广教授课题组在Clinical and Translational Medicine（IF = 11.49）上正式发表了题为“MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-...
重庆医科大学感染性疾病分子生物学教育部重点实验室肝癌研究成果在《Journal of Clinical Investigation》发表（图）
重庆医科大学 感染性疾病分子生物学 教育部 重点实验室 肝癌 研究成果 Journal of Clinical Investigation
2021/3/11
近日，我校感染性疾病分子生物学教育部重点实验室在代谢紊乱与肝癌进展的研究中取得重要突破，向进博士、陈昶副研究员、刘芮博士和苟冬梅博士作为并列第一作者的研究成果“Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose depr...
呼吸疾病国家重点实验室在欧洲临床微生物和传染病学会官方杂志Clinical Microbiology and Infection发表临床结核菌耐药研究成果（图）
临床；微生物；传染病学会；结核菌
2021/10/9
近日，欧洲临床微生物和传染病学会的官方杂志Clinical Microbiology and Infection（影响因子：5.394）发表了实验室张天宇课题组与广州市胸科医院（实验室结核病研究室PI谭耀驹主任）及香港中文大学等合作单位有关“我国临床耐药结核病‘结核菌株存在严重的异烟肼与丙硫异烟胺交叉耐药’”课题的最新研究成果“Detection of novel mutations associ...
Erratum for Maki et al. Consumption of a cranberry juice beverage lowered the number of clinical urinary tract infection episodes in women with a recent history of urinary tract infection. Am J Clin Nutr 2016;103:1434–42.
Erratum Consumption of a cranberry juice episode
2018/11/16
Erratum for Maki et al. Consumption of a cranberry juice beverage lowered the number of clinical urinary tract infection episodes in women with a recent history of urinary tract infection. Am J Clin N...
Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial
green tea EGCG blood lipids postmenopausal cardiovascular randomized controlled trial
2018/12/19
Background: Green tea has been suggested to improve cardiovascular disease risk factors, including circulating lipid variables. However, current evidence is predominantly based on small, short-term ra...
Randomized clinical trial on the efficacy of hesperidin 2S on validated cardiovascular biomarkers in healthy overweight individuals
blood pressure endothelial function hesperidin obesity polyphenols
2018/12/19
Background: Endothelial dysfunction (ED) is involved in the development of atherosclerosis. Hesperidin, a citrus flavonoid with antioxidant and other biological properties, potentially exerts benefici...
Potatoes and risk of obesity, type 2 diabetes, and cardiovascular disease in apparently healthy adults: a systematic review of clinical intervention and observational studies
adiposity french fry glycemic index potato solanum tuberosum
2018/12/13
Background: Potatoes have been related to increased risks of obesity, type 2 diabetes (T2D), and cardiovascular disease (CVD) mainly because of their high glycemic index.
Project Management of Randomized Clinical Trials:A Narrative Review
Clinical Trial Project Management Trial Manager Principal Investigator Study Protocol
2015/11/9
Context: A well-structured protocol for a clinical trial may be able to answer clinical questions, but it cannot be deemed enough to ensure success in the face of incompetent management of time as wel...
Clinical Determinants of Left Ventricular Ejection Fraction Deterioration in Patients Suffered From Complete Left Bundle Branch Block
Bundle-Branch Block Coronary Artery Left Ventricular Ejection Fraction
2015/10/20
Background: Recently, the deleterious effects of left bundle branch block (LBBB) on left ventricular systolic function have been taken into consideration.
Comparison of the Effects of Eicosapentaenoic Acid With Docosahexaenoic Acid on the Level of Serum Lipoproteins in Helicobacter pylori:A Randomized Clinical Trial
Helicobacter pylori Eicosapentaenoic Acid Docosahexaenoic Acid Cholesterol Triglyceride
2015/10/16
Background: Helicobacter pylori infection is the most common chronic bacterial infection around the world and an important cause of gastrointestinal disorders, which might be involved in the pathogene...
Methods of Assessment and Clinical Relevance of QT Dynamics
QT interval ventricular repolarisation QT dynamics arrhythmic risk QT interval prolongation
2015/7/31
The dependence on heart rate of the QT interval has been investigated for many years and several mathematical formulae have been proposed to describe the QT interval/heart rate (or QT interval/RR inte...
Getting Under the Skin of Clinical Inertia in Insulin Initiation: The Translating Research Into Action for Diabetes (TRIAD) Insulin Starts Project
diabetes insulin therapy clinical inertia clinical decision-making
2014/12/11
Purpose The purpose of this cross-sectional study is to explore primary care providers’ (PCPs) perceptions about barriers to initiating insulin among patients. Studies suggest that many patients with ...
The Assessment of Undergraduate Medical Students’ Satisfaction Levels With the Objective Structured Clinical Examination
Undergraduate Medical Students Internal Medicine Personal Satisfaction
2015/10/14
Background: The objective structured clinical examination (OSCE) has been introduced as an efficient method for the assessment of medical students.
Prevalence and Clinical Picture of Musculoskeletal Sarcoidosis
Sarcoidosis Arthritis Musculoskeletal Diseases
2015/10/13
Background: Sarcoidosis is a multisystem disease affecting different organs with different frequency rates depending on geographical location. Musculoskeletal abnormalities includes osseous lesions (s...
Nocardiosis:Risk Factors, Clinical Characteristics and Outcome
Nocardia Infections Immunocompromised Host Treatment Outcome Nocardiosis Cutaneous
2015/10/12
Nocardiosis has been reported increasingly in recent two decades, probably due to improvement in isolation of the organism and increased burden of immune compromised patients. Nocardia occasionally ha...