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Antibody's unusual abilities might inspire vaccine strategies
Antibody's unusual abilities inspire vaccine strategies
2015/5/25
The recent discovery of a novel antibody that works in an unusual way might inspire ideas for designing more effective vaccines. Among the common pathogens that might be targeted ...
Antibodies are a family of glycoproteins that bind specifically to foreign molecules (antigens). The binding between antibodies and antigens has high specificity and affinity resulting from various st...
Levels of Haemophilus influenzae type B (Hib) antibody in Turkey before routine immunization
Haemophilus influenzae type b antibody serosurveillance
2010/12/21
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introductio...
Evaluation of tumor targeting with radiolabeled F(ab)2 fragment of a humanized monoclonal antibody
Humanized monoclonal antibody F(ab)2 fragment I-125
2010/1/6
Humanized monoclonal antibody U36 and its F(ab')2 fragment, radio labeled with 125I, were tested for tumor localization in nude mice bearing a squamous cell carcinoma xenograft line derived from a hea...
DETERMINATION OF THE LEVEL OF ANTIBODY TO RUBELLA IN FEMALE STUDENTS
Epidemiological studies Antibody level Vaccinated individuals
2009/12/30
There are few published reports on epidemiological studies concerning Rubella in Iran. The level of antibody in vaccinated individual’s declines gradually and the chances of infection in these people ...
Autosomal Recessive Chronic Granulomatous Disease,IgA Deficiency and Refractory Autoimmune Thrombocytopenia Responding to Anti-CD20 Monoclonal Antibody
Anti-CD20 Autoimmune thrombocytopenia Chronic granulomatous disease IgA deficiency Primary immunodeficiency diseases
2009/12/17
Immunodeficiency and autoimmune disease may occur concomitantly in the same individual. Some of the immunodeficiency syndromes, especially humoral defects are associated with autoimmune disorders. Hem...
《Current Trends in Monoclonal Antibody Development and Manufacturing》（图）
Current Trends in Monoclonal Antibody Development and Manufacturing Steven J. Shire Wayne Gombotz Karoline Bechtold-Peters James Andya
2013/12/4
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years...
A new computer model developed at MIT can help solve a problem that has plagued drug companies trying to develop promising new treatments made of antibodies: Such drugs have a relatively short shelf l...
Production of Monoclonal Antibody Specific for Human Hemoglobin
Institue for Genetic Engineering and Biotechnology,TÜ Bİ TAK Marmara Research Center,Gebze,Kocaeli Department of Medical Biology,Faculty of Medicine,Marmara University,İ stanbul-TURKEY
2009/6/29
Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually impli...
Measurement of Urine Albumin Levels With A Monoclonal Antibody Based in-House Elisa
Human albumin Monoclonal antibody Polyclonal antibody ELISA
2009/6/25
Microalbuminuria is considered to be an early indicator of diabetic nephropathy. We have previously reported the establishment of A-HAlb/98 hybridoma secreting monoclonal antibody that specifically re...
Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice
aged mouse immunosuppression phospholipase A2 restraint stress specific antibody
2010/11/16
Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis. Although age-related ...
Drug-induced Hypersensitivity Syndrome Associated with a Marked Increase in Anti-paramyxovirus Antibody Titers in a Scleroderma Patient
cyclophosphamide drug hypersensitivity mumps virus parainfluenza virus sulfamethoxazole/trimethoprim
2010/11/18
Background: Drug-induced hypersensitivity syndrome (DIHS) is characterized by a severe multiorgan hypersensitivity reaction that usually appears after prolonged exposure to certain drugs and may be re...
Detection of Mycobacterial antigen and antibody in
Tuberculosis PPD Antituberculous antibody Reverse passive hemagglutination
2015/9/9
Background: Little is known about changes in total antibodies occurring during the progression of tuberculosis or its treatment. Using passive and reverse passive hemagglutination methods, mycobacteri...
Application of Radioimmunoassay Technique for Determination of Antigen Concentration in Different Cells with a New Monoclonal Antibody
PET/CT X-ray CT Attenuation correction CTAC Hybrid imaging Contrast medium Artifact
2010/2/8
Introduction: Binding a monoclonal antibody to tumor associated antigens is an effective method for cancer therapy because these agents can specifically target malignant cells, in fact monoclonal anti...
High Production of IL-18 by Dendritic Cells Induced by Sera from Patients with Primary Antibody Deficiency
Common variable immunodeficiency Interleukin-18 X-linked agammaglobulinemia
2010/4/8
Predominantly antibody deficiencies are a category of primary immunodeficiency diseases, which
consist of several rare disorders such as common variable immunodeficiency (CVID) and X-linked agammaglo...